Since the 1960s, it has been known that the sputum of CF patients can antagonize the
bioactivity of antibiotics such as neomycin and polymyxin. 15, 29 Aerosol antibiotic …

Aerosol antibiotics in control studies have been shown to improve lung function and reduce
the number of acute hospital admissions in patients with cystic fibrosis (CF). However, their …

Aerosol administration of antipseudomonal antibiotics is commonly used in cystic fibrosis.
However, its contribution to the improvement of lung function, infection and quality of life is …

Inhaled antibiotics offer an attractive alternative to systemic administration in cystic fibrosis
(CF) for several reasons. Antibiotics can be administered directly to the site of infection with …

OBJECTIVE: To provide an overview of aerosol drug therapy, including physical
considerations and aerosol drug delivery systems, and to review clinical experience with …

Early studies of the use of antibiotics in patients with cystic fibrosis suggested that they
would be of benefit in preventing or reducing infection by Pseudomonas aeruginosa. In …

ABSTRACT1 Aerosolized antibiotics have been shown to be a useful modality of treatment
in patients with cystic fibrosis. In this investigation we examined the utility of this treatment in …

In cystic fibrosis (CF), the clinical effectiveness of aerosolized antibiotics is controversial.
Previous investigators have not considered the type of nebulizer, droplet size, and dose to …

There are strong data supporting using the use of aerosolized antibiotics for the treatment of
Gram-negative infections in patients with cystic fibrosis (CF). The regular use of aerosol …

Antibiotics are administered to patients with cystic fibrosis to eliminate or suppress sputum
bacteria. Aerosol administration is attractive because it delivers antibiotic directly to the site …