Role of renin angiotensin system inhibitors in cardiovascular and renal protection: a lesson from clinical trials
L Stojiljkovic, R Behnia - Current pharmaceutical design, 2007 - ingentaconnect.com
Beneficial effects of angiotensin converting enzyme inhibitors (ACEI) and angiotensin type 1
receptor (AT1) blockers in patients with cardiovascular and renal diseases have been …
receptor (AT1) blockers in patients with cardiovascular and renal diseases have been …
Angiotensin-converting enzyme inhibitors versus AT1 receptor antagonist in cardiovascular and renal protection: the case for AT1 receptor antagonist
T Berl - Journal of the American Society of Nephrology, 2004 - journals.lww.com
The development of pharmacologic agents that directly inhibit the angiotensin II receptor
(angiotensin receptor blocker [ARB]) has provided clinicians with an alternative to the …
(angiotensin receptor blocker [ARB]) has provided clinicians with an alternative to the …
AT1 receptor antagonists: a challenge for ACE inhibitors in diabetic nephropathy
A Mogyorósi, S Sonkodi - Diabetes/metabolism research and …, 1999 - Wiley Online Library
Due to its hemodynamic, metabolic and growth promoting effects, angiotensin II (AII) may
play an important role in the pathogenesis of diabetic kidney disease. Consequently …
play an important role in the pathogenesis of diabetic kidney disease. Consequently …
Renin angiotensin blockers and cardiac protection: from basics to clinical trials
Despite a similar beneficial effect on blood pressure lowering observed with angiotensin-
converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor (AT1R) blocker …
converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor (AT1R) blocker …
Angiotensin receptor blockers: therapeutic targets and cardiovascular protection
In the prevention and treatment of cardiovascular disease, pharmacological treatment
strategies should have several aims:(i) in individuals without overt cardiovascular disease …
strategies should have several aims:(i) in individuals without overt cardiovascular disease …
Angiotensin receptor blockers and the kidney: possible advantages over ACE inhibition?
ME Cooper, RL Webb… - Cardiovascular drug …, 2001 - Wiley Online Library
This review deals with similarities and differences between the effects of ACE inhibitors and
AT1‐receptor blockers in the kidney. Specific receptor blockade has demonstrated that the …
AT1‐receptor blockers in the kidney. Specific receptor blockade has demonstrated that the …
Cardiovascular protection with ace inhibitors--more HOPE for EUROPA?
CJ Boos - Medical Science Monitor: International Medical Journal …, 2004 - europepmc.org
Background Treatment with angiotensin converting enzyme (ACE) inhibitors reduces
mortality and morbidity among patients with heart failure, left-ventricular dysfunction after …
mortality and morbidity among patients with heart failure, left-ventricular dysfunction after …
Mechanism of action of angiotensin-receptor blocking agents
HM Siragy, M Bedigian - Current Hypertension Reports, 1999 - Springer
Angiotensin II is the most active hormone of the reninangiotensin system. In humans, two
angiotensin receptors have been identified: AT 1 and AT 2. In adults, most of the effects of …
angiotensin receptors have been identified: AT 1 and AT 2. In adults, most of the effects of …
Mega clinical trials which have shaped the RAS intervention clinical practice
R Düsing - Therapeutic advances in cardiovascular disease, 2016 - journals.sagepub.com
Following extensive clinical research, drugs affecting the renin–angiotensin system have
been used for the treatment of patients with congestive heart failure, myocardial infarction …
been used for the treatment of patients with congestive heart failure, myocardial infarction …
Angiotensin receptor blockers: role in hypertension management, cardiovascular risk reduction, and nephropathy.
J Basile, PP Toth - Southern Medical Journal, 2009 - europepmc.org
Background The renin-angiotensin system (RAS) plays a central pathogenic role in the
development of hypertension and associated vascular disorders. However, whether the two …
development of hypertension and associated vascular disorders. However, whether the two …