Isolation of atherogenic modified (desialylated) low density lipoprotein from blood of atherosclerotic patients: separation from native lipoprotein by affinity …
VV Tertov, IA Sobenin, AG Tonevitsky… - Biochemical and …, 1990 - Elsevier
A part of low density lipoproteins (LDL) isolated from the blood of healthy subjects and
patients with coronary atherosclerosis bind to a Sepharose-linked Ricinus communis …
patients with coronary atherosclerosis bind to a Sepharose-linked Ricinus communis …
Modified (desialylated) low-density lipoprotein measured in serum by lectin-sorbent assay
VV Tertov, IA Sobenin, AN Orekhov - Clinical Chemistry, 1995 - academic.oup.com
Modified low-density lipoprotein (LDL) with a low sialic acid content was found in the blood
of patients with coronary atherosclerosis. This desialylated lipoprotein causes lipid …
of patients with coronary atherosclerosis. This desialylated lipoprotein causes lipid …
Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells: discovery of desialylated lipoprotein with altered cellular metabolism …
AN Orekhov, VV Tertov, DN Mukhin… - Biochemical and …, 1989 - Elsevier
Low density lipoprotein (LDL) isolated from the blood of healthy donors was partially
desialylated by incubating the lipoprotein with sialidase (neuraminidase). The addition of …
desialylated by incubating the lipoprotein with sialidase (neuraminidase). The addition of …
Characterization of desialylated low-density lipoproteins which cause intracellular lipid accumulation.
VV Tertov, IA Sobenin, AN Orekhov - International journal of tissue …, 1992 - europepmc.org
The properties of sialylated (sialic acid rich) and desialylated (sialic acid poor) fractions of
low-density lipoproteins (LDL) isolated from blood plasma of healthy subjects and coronary …
low-density lipoproteins (LDL) isolated from blood plasma of healthy subjects and coronary …
Desialylated low density lipoprotein-naturally occurring modified lipoprotein with atherogenic potency
AN Orekhov, VV Tertov, DN Mukhin - Atherosclerosis, 1991 - Elsevier
We have recently established that low density lipoprotein (LDL) of most patients with
coronary atherosclerosis differs from the LDL of most healthy subjects by its ability to cause …
coronary atherosclerosis differs from the LDL of most healthy subjects by its ability to cause …
Naturally occurring modified low density lipoproteins are similar if not identical: more electronegative and desialylated lipoprotein subfractions
VV Tertov, G Bittolo-Bon, IA Sobenin… - Experimental and …, 1995 - Elsevier
Previous studies demonstrated that more electronegative low density lipoprotein (LDL)
isolated from human blood by ion exchange chromatography has a chemical composition …
isolated from human blood by ion exchange chromatography has a chemical composition …
Low-density lipoprotein modification occurring in human plasma: Possible mechanism of in vivo lipoprotein desialylation as a primary step of atherogenic modification
VV Tertov, VV Kaplun, IA Sobenin, AN Orekhov - Atherosclerosis, 1998 - Elsevier
We previously found in human blood a fraction of low-density lipoprotein (LDL) that is
characterized by a reduced content of sialic acid. Desialylated LDL also has a low neutral …
characterized by a reduced content of sialic acid. Desialylated LDL also has a low neutral …
Three types of naturally occurring modified lipoproteins induce intracellular lipid accumulation due to lipoprotein aggregation.
VV Tertov, AN Orekhov, IA Sobenin… - Circulation …, 1992 - Am Heart Assoc
Low density lipoprotein (LDL) from patients with coronary atherosclerosis and diabetes
mellitus as well as in vitro desialylated LDL, glycosylated LDL, and lipoprotein (a) caused a …
mellitus as well as in vitro desialylated LDL, glycosylated LDL, and lipoprotein (a) caused a …
Multiple-modified desialylated low density lipoproteins that cause intracellular lipid accumulation. Isolation, fractionation and characterization.
VV Tertov, IA Sobenin, ZA Gabbasov… - … ; a Journal of …, 1992 - europepmc.org
Background The basic differences between sialylated (sialic acid rich) and desialylated
(sialic acid poor) human low density lipoproteins (LDL) are not fully defined. It is not known …
(sialic acid poor) human low density lipoproteins (LDL) are not fully defined. It is not known …
Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits.
A Daugherty, BS Zweifel, BE Sobel… - … : An Official Journal of …, 1988 - Am Heart Assoc
Atherogenic properties of low density lipoproteins (LDL) in vivo may reflect modification of
lipoproteins associated with endothelial translocation and exposure to extracellular matrix …
lipoproteins associated with endothelial translocation and exposure to extracellular matrix …