Abstract Objective Bile acids (BAs) facilitate fat absorption and may play a role in glucose
and metabolism regulation, stimulating the secretion of gut hormones. The relative …

Bile acids play essential roles in the absorption of dietary lipids and in the regulation of bile
acid biosynthesis. Recently, a G protein-coupled receptor, TGR5, was identified as a cell …

Glucagon‐like peptide‐1 (GLP‐1) and peptide YY (PYY), secreted by enteroendocrine L‐
cells located most densely in the colon and rectum, are of fundamental importance in blood …

Bile acids (BAs) are signalling molecules that mediate various cellular responses in both
physiological and pathological processes. Several studies report that BAs can be detected …

A large number of glucagon-like-peptide-1 (GLP-1)-and peptide-YY (PYY)-producing L cells
are located in the colon, but little is known about their contribution to whole body …

Bile acids (BAs), the end products of cholesterol catabolism, are essential for the absorption
of lipids and fat-soluble vitamins; but they have also emerged as novel signaling molecules …

Bile acids (BA), long believed to only have lipid-digestive functions, have emerged as novel
metabolic modulators. They have important endocrine effects through multiple cytoplasmic …

Bile acid sequestrants have been used for decades for the treatment of
hypercholesterolaemia. Sequestering of bile acids in the intestinal lumen interrupts …

BACKGROUND AND PURPOSE The glucagon‐like peptides GLP‐1 and GLP‐2 are
secreted from enteroendocrine L‐cells following nutrient ingestion. Drugs that increase …

In addition to their role in the digestion and absorption of dietary fats, bile acids (BAs) are
tightly regulated signalling molecules. Their levels in the intestinal lumen, circulation and …