Amorphous solid dispersions of BCS class II drugs: a rational approach to solvent and polymer selection
Miniaturised solvent casting (MSC) has been developed as a method for screening the
stability of amorphous solid dispersions (ASD) of BCS class II drugs. The aim of the work …
stability of amorphous solid dispersions (ASD) of BCS class II drugs. The aim of the work …
Amorphous solid dispersions: Rational selection of a manufacturing process
Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
[HTML][HTML] Solvent influence on the phase behavior and glass transition of Amorphous Solid Dispersions
S Dohrn, C Luebbert, K Lehmkemper… - European Journal of …, 2021 - Elsevier
Understanding the long-term stability of amorphous solid dispersions (ASDs) is important for
their successful approval for market. ASD stability does not only depend on the interplay …
their successful approval for market. ASD stability does not only depend on the interplay …
Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products
Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations
SK Saha, A Joshi, R Singh, K Dubey - Pharmaceutical …, 2023 - Taylor & Francis
Evolving therapeutic landscape through combinatorial chemistry and high throughput
screening have resulted in an increased number of poorly soluble drugs. Drug delivery …
screening have resulted in an increased number of poorly soluble drugs. Drug delivery …
Effects of the preparation process on the properties of amorphous solid dispersions
S Huang, RO Williams - Aaps Pharmscitech, 2018 - Springer
The use of amorphous solid dispersions to improve the bioavailability of active ingredients
from the BCS II and IV classifications continues to gain interest in the pharmaceutical …
from the BCS II and IV classifications continues to gain interest in the pharmaceutical …
[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
The role of the carrier in the formulation of pharmaceutical solid dispersions. Part II: amorphous carriers
T Van Duong, G Van den Mooter - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Amorphous solid dispersions are considered as one of the most powerful
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …
strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical …
New strategies for improving the development and performance of amorphous solid dispersions
The understanding of amorphous solid dispersions has grown significantly in the past
decade. This is evident from the number of approved commercial amorphous solid …
decade. This is evident from the number of approved commercial amorphous solid …
Evaluation on the drug–polymer mixing status in amorphous solid dispersions at the early stage formulation and process development
H Ma, DS Choi, YE Zhang, H Tian, N Shah… - Journal of …, 2013 - Springer
Drug and polymer mixing status in amorphous solid dispersions, an important aspect with
regard to the physical stability and in vivo performance of such systems, was evaluated in …
regard to the physical stability and in vivo performance of such systems, was evaluated in …