Background Prior studies have suggested a potential relationship between osteoporosis
and sarcopenia, both of which can present symptoms of compromised mobility. Additionally …

Background Osteoporosis and sarcopenia are common age-related conditions
characterized by the progressive loss of bone density and muscle mass, respectively. Their …

Osteosarcopenia is a geriatric syndrome coexistence of osteoporosis and sarcopenia.
However, the molecular mechanism underlying osteosarcopenia have not been fully …

Background The purpose of this study was to report the RNA sequencing profile according
to the presence or absence of sarcopenia in elderly patients with osteoporotic hip fracture …

Objective This study aimed to identify osteoporosis-related core genes using bioinformatics
analysis and machine learning algorithms. Methods mRNA expression profiles of …

Background Osteoporosis (OP) is increasingly prevalent with the aging of the world
population. It is urgent to identify efficient diagnostic signatures for the clinical application …

In this study, we integrated large-scale GWAS summary data and used the predicted
transcriptome-wide association study method to discover novel genes associated with …

Background Postmenopausal osteoporosis, a common yet chronic systemic metabolic
disease, has become a major public health problem due to life expectancy increasing …

Aims This study explored the shared genetic traits and molecular interactions between
postmenopausal osteoporosis (POMP) and sarcopenia, both of which substantially degrade …

Osteoporosis is a progressive bone disease in the elderly and lacks an effective
classification method of patients. This study constructed a gene signature for an accurate …