In this Special Issue of Genes entitled “Genetic Conditions Affecting the Skeleton:
Congenital, Idiopathic Scoliosis and Arthrogryposis”, evidence is presented which suggests …

Background Adolescent idiopathic scoliosis (AIS) is a complex genetic disorder that causes
spinal deformity in approximately 3% of the population. Candidate gene, linkage, and …

In EBioMedicine, Meng et al. reported a genome-wide methylation analysis for curve
progression of adolescent idiopathic scoliosis (AIS)(Meng et al.[1]). They examined DNA …

Abstract Purpose Adolescent Idiopathic Scoliosis (AIS) is considered a complex genetic
disease, in which malfunctioning or dysregulation of one or more genes has been proposed …

The etiology of familial idiopathic scoliosis remains in question. The role of genetic factors in
the development of this disorder has been well-documented; however, reports of the specific …

Objective. To analyze the current literature dedicated to the etiopathogenesis and
development of idiopathic scoliosis. Material and Methods. The analysis includes studies on …

Adolescent Idiopathic Scoliosis (AIS) is a prevalent and important spine disorder in the
pediatric age group. An increased family tendency was observed for a long time, but the …

A significant genetic involvement has been known for decades to exist in adolescent
idiopathic scoliosis (AIS), a spine deformity affecting 1–3% of the world population …

Scoliosis represents the most common musculoskeletal disorder in children and affects
approximately 3% of the world population. Scoliosis is separated into two major phenotypic …

Idiopathic scoliosis (IS) is the most common pediatric spinal deformity, affecting 2–3% of
school age children worldwide. This disease is typically classified by age at onset, with the …