We evaluated 7 C. muridarum ORFs for their ability to induce protection against chlamydial
infection in a mouse intravaginal infection model. These antigens, although encoded in C …

We have previously shown that the plasmid-encoded Pgp3 is a major virulence factor for C.
muridarum induction of hydrosalpinx. We now report that Pgp5 also plays a significant role …

Despite the extensive efforts, there is still a lack of a licensed vaccine against Chlamydia
trachomatis in humans. The mouse genital tract infection with Chlamydia muridarum has …

Hydrosalpinx induction in mice by Chlamydia muridarum infection, a model that has been
used to study C. trachomatis pathogenesis in women, is known to depend on the cryptic …

Intravaginal infection with plasmid-competent but not plasmid-free Chlamydia muridarum
induces hydrosalpinx in mouse upper genital tract, indicating a critical role of the plasmid in …

Chlamydia muridarum has been used to study chlamydial pathogenesis because it induces
mice to develop hydrosalpinx, a pathology observed in C. trachomatis-infected women. We …

Chlamydia infection remains the leading sexually‐transmitted bacterial infection worldwide,
causing damaging sequelae such as tubal scarring, infertility and ectopic pregnancy. As …

Chlamydia trachomatis is a pathogen of the genital tract and ocular epithelium. Infection is
established by the binding of the metabolically inert elementary body (EB) to epithelial cells …

Chlamydia trachomatis is the most common bacterial sexually transmitted disease in the
world and specifically in the United States, with the highest incidence in age-groups 14–19 …

We previously reported that 5 Chlamydia muridarum antigens reacted with antisera from>
90% mice urogenitally infected with C. muridarum and they are TC0660 (ABC transporter or …