[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment

K Grzesik, M Janik, D Hoja-Łukowicz - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Abstract Changes in the glycosylation process appear early in carcinogenesis and evolve
with the growth and spread of cancer. The correlation of the characteristic glycosylation …

Glycomic approaches for the discovery of targets in gastrointestinal cancer

S Mereiter, M Balmaña, J Gomes, A Magalhães… - Frontiers in …, 2016 - frontiersin.org
Gastrointestinal (GI) cancer is the most common group of malignancies and many of its types
are among the most deadly. Various glycoconjugates have been used in clinical practice as …

Glycosylation and cancer: moving glycomics to the forefront

RR Drake - Advances in cancer research, 2015 - Elsevier
There is a long research history of studying the function of glycosylation in relation to the
development and progression of different types of cancer. The technological advances of the …

Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques

Y Haga, K Ueda - Glycoconjugate Journal, 2022 - Springer
Despite significant worldwide investment in research, cancer remains one of the most
common cause of death in the world. Early detection and reliable diagnosis are the keys to …

Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

Alterations in glycosylation as biomarkers for cancer detection

CA Reis, H Osorio, L Silva, C Gomes… - Journal of clinical …, 2010 - jcp.bmj.com
Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …

Decoding the glycoproteome: a new frontier for biomarker discovery in cancer

K He, M Baniasad, H Kwon, T Caval, G Xu… - Journal of Hematology & …, 2024 - Springer
Cancer early detection and treatment response prediction continue to pose significant
challenges. Cancer liquid biopsies focusing on detecting circulating tumor cells (CTCs) and …

Glycans as cancer biomarkers

B Adamczyk, T Tharmalingam, PM Rudd - Biochimica et Biophysica Acta …, 2012 - Elsevier
BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …

Altered glycosylation in tumours focused to cancer diagnosis

R Peracaula, S Barrabés, A Sarrats, PM Rudd… - Disease …, 2008 - content.iospress.com
The lack of specific and sensitive tumour markers for early detection of cancer is driving a
search for new approaches that could identify biomarkers. Markers are needed to alert …

Glycosylation and metastases

D Josic, T Martinovic, K Pavelic - Electrophoresis, 2019 - Wiley Online Library
The change of cellular glycosylation is one of the key events in malignant transformation and
neoplastic progression, and tumor‐related glycosylation alterations are promising targets in …