Deficiency of a novel retinoblastoma binding protein 2-homolog is a consistent feature of sporadic human melanoma skin cancer.

T Vogt, M Kroiss, M McClelland, C Gruss… - … ; a Journal of …, 1999 - europepmc.org
Using RNA arbitrarily primed PCR, the authors selected for transcripts with cell cycle-related
differential expression in cultured human melanocytes. Among the partial cDNAs cloned, a …

[HTML][HTML] Retinoblastoma-binding protein 2-homolog 1: a retinoblastoma-binding protein downregulated in malignant melanomas

A Roesch, B Becker, S Meyer, P Wild, C Hafner… - Modern Pathology, 2005 - Elsevier
In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of
retinoblastoma protein (pRb)-activity. Members of the previously described family of …

Isolation and chromosomal localization of a new human retinoblastoma binding protein 2 homologue 1a (RBBP2H1A)

V Kashuba, A Protopopov, R Podowski… - European Journal of …, 2000 - nature.com
Using a NotI linking clone NR-025 as a probe, we isolated a novel putative member of the
RB binding protein family, namely a human retinoblastoma binding protein 2 homologue …

RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis

J Cao, T Gao, EJ Stanbridge… - Journal of the National …, 2001 - academic.oup.com
Background: Antibodies isolated from cancer patients have been used to identify genes
encoding tumor-associated antigen epitopes relevant to immune responses in cancer …

[HTML][HTML] Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells

A Roesch, B Becker, W Schneider-Brachert… - Journal of investigative …, 2006 - Elsevier
The loss of cell cycle control in malignant melanomas is thought to be due to a lack of
retinoblastoma protein (pRb) activity. We have recently reported a progressive deficiency of …

Immunohistochemical expression of retinoblastoma protein in cutaneous melanomas

MC Saenz‐Santamaria, NS McNutt… - British Journal of …, 1995 - academic.oup.com
Retinoblastoma protein (pRB) is the product of a tumour‐suppressor gene (rb) mapped to
chromosome 1 3q14. pRB acts as a control checkpoint at the G1 phase of the cell cycle …

cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product

Y Sakai, M Saijo, K Coelho, T Kishino, N Niikawa… - Genomics, 1995 - Elsevier
We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …

Cloning and expression of a novel retinoblastoma binding protein cDNA, RBBP10

JZ Chen, QS Yang, S Wang, XF Meng, K Ying, Y Xie… - Biochemical …, 2002 - Springer
A 2860-bp cDNA was isolated from a human fetal brain cDNA library by high throughput
cDNA sequencing, which encodes a putative protein with 186 amino acids. The putative …

Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites.

GA Otterson, RA Kratzke, AY Lin, PG Johnston… - Oncogene, 1993 - europepmc.org
We have isolated cDNA and genomic clones for the human retinoblastoma binding protein 1
(RBP1) gene, and have identified alternative splicing of RBP1 clustered within a 207 …

RB1 oncosuppressor gene over-expression inhibits tumor progression and induces melanogenesis in metastatic melanoma cells.

P Valente, A Melchiori, MG Paggi, L Masiello, D Ribatti… - Oncogene, 1996 - europepmc.org
The retinoblastoma gene (RB1) is frequently deleted or mutated in many tumor types and in
all cases of retinoblastoma. Apart from its role in regulation of the cell cycle, the RB1 gene …