Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

B Parrino, D Schillaci, I Carnevale, E Giovannetti… - European journal of …, 2019 - Elsevier
Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

Novel approaches to combat bacterial biofilms

C Beloin, S Renard, JM Ghigo, D Lebeaux - Current opinion in …, 2014 - Elsevier
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …

Natural anti-biofilm agents: strategies to control biofilm-forming pathogens

R Mishra, AK Panda, S De Mandal, M Shakeel… - Frontiers in …, 2020 - frontiersin.org
Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …

[HTML][HTML] Bacterial biofilm eradication agents: a current review

AD Verderosa, M Totsika, KE Fairfull-Smith - Frontiers in chemistry, 2019 - frontiersin.org
Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

An overview of biofilm formation–combating strategies and mechanisms of action of antibiofilm agents

ST Asma, K Imre, A Morar, V Herman, U Acaroz… - Life, 2022 - mdpi.com
Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …

Antibiofilm agents: A new perspective for antimicrobial strategy

XH Li, JH Lee - Journal of Microbiology, 2017 - Springer
Biofilms are complex microbial architectures that attach to surfaces and encase
microorganisms in a matrix composed of self-produced hydrated extracellular polymeric …

Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance

S Nadar, T Khan, SG Patching, A Omri - Microorganisms, 2022 - mdpi.com
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

Small molecule anti-biofilm agents developed on the basis of mechanistic understanding of biofilm formation

K Qvortrup, LD Hultqvist, M Nilsson… - Frontiers in …, 2019 - frontiersin.org
Microbial biofilms are the cause of persistent infections associated with various medical
implants and distinct body sites such as the urinary tract, lungs, and wounds. Compared with …

Strategies for interfering with bacterial early stage biofilms

J Fu, Y Zhang, S Lin, W Zhang, G Shu, J Lin… - Frontiers in …, 2021 - frontiersin.org
Biofilm-related bacteria show high resistance to antimicrobial treatments, posing a
remarkable challenge to human health. Given bacterial dormancy and high expression of …