An introduction to TRP channels
IS Ramsey, M Delling, DE Clapham - Annu. Rev. Physiol., 2006 - annualreviews.org
▪ Abstract The aim of this review is to provide a basic framework for understanding the
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels
The transient receptor potential (TRP1) ion channels are named after the role of the
channels in Drosophila phototransduction. The mammalian genes are encoded by at least …
channels in Drosophila phototransduction. The mammalian genes are encoded by at least …
TRP channels: emerging targets for respiratory disease
KH Banner, F Igney, C Poll - Pharmacology & therapeutics, 2011 - Elsevier
The mammalian transient receptor potential (TRP) superfamily of cation channels is divided
into six subfamilies based on sequence homology TRPC (canonical), TRPV (vanilloid) …
into six subfamilies based on sequence homology TRPC (canonical), TRPV (vanilloid) …
TRP channels: potential drug target for neuropathic pain
Neuropathic pain is a debilitating disease which affects central as well as peripheral
nervous system. Transient receptor potential (TRP) channels are ligand-gated ion channels …
nervous system. Transient receptor potential (TRP) channels are ligand-gated ion channels …
Transient receptor potential channels and calcium signaling
L Vangeel, T Voets - Cold Spring Harbor perspectives in …, 2019 - cshperspectives.cshlp.org
Transient receptor potential (TRP) cation channels play diverse roles in cellular Ca2+
signaling. First, as Ca2+-permeable channels that respond to a variety of stimuli, TRP …
signaling. First, as Ca2+-permeable channels that respond to a variety of stimuli, TRP …
TRP channels as potential drug targets
MM Moran - Annual review of pharmacology and toxicology, 2018 - annualreviews.org
The transient receptor potential (TRP) superfamily of channels comprises a diverse group of
cation channels. Four TRP channel subunits coassemble to form functional homo-or …
cation channels. Four TRP channel subunits coassemble to form functional homo-or …
[HTML][HTML] TRPV4: a physio and pathophysiologically significant ion channel
T Rosenbaum, M Benítez-Angeles… - International journal of …, 2020 - mdpi.com
Transient Receptor Potential (TRP) channels are a family of ion channels whose members
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …
Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions
Members of the transient receptor potential (TRP) family of nonselective cation channels are
involved in several pathological and physiological conditions. The search for the molecular …
involved in several pathological and physiological conditions. The search for the molecular …
Transient receptor potential channels: targeting pain at the source
A Patapoutian, S Tate, CJ Woolf - Nature reviews Drug discovery, 2009 - nature.com
Pain results from the complex processing of neural signals at different levels of the central
nervous system, with each signal potentially offering multiple opportunities for …
nervous system, with each signal potentially offering multiple opportunities for …
[HTML][HTML] TRP channels role in pain associated with neurodegenerative diseases
M Duitama, V Vargas-López, Z Casas… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …