The identification of serum biomarkers has lead to improvements in the detection and
diagnosis of cancer, and combinations of these biomarkers have increased further their …

BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …

Cancer is the second most common cause of death in developed countries with
approximately 14 million newly diagnosed individuals and over 6 million cancer‐related …

Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted
by cancer cells is a potential source of disease biomarkers and provides insights into …

Proteins are routinely measured in clinical laboratories for diagnosis, prognosis and therapy
monitoring. Nevertheless, both test improvements (performance) and innovations …

Glycosylation is a diverse but critically important post-translational modification that
modulates the physical, chemical and biological properties of proteins. Alterations in …

Lung cancer has a poor prognosis and a 5-year survival rate of 15%. Therefore, early
detection is vital. Diagnostic testing of serum for cancer-associated biomarkers is a …

Background: Glycosylated proteins play important roles in cell-to-cell interactions,
immunosurveillance, and a variety of receptor-mediated and specific protein functions …

Detection of cancer at early stages that can be treated through surgery is a difficult task. One
methodology for cancer biomarker discovery exploits the fact that glycoproteins produced by …

Protein glycosylation has been implicated in key biological processes including
immunological recognition, cellular adhesion, protein folding, and signaling as well as …