RBC transfusion improves cerebral oxygen delivery in subarachnoid hemorrhage

R Dhar, AR Zazulia, CP Derdeyn… - Critical care …, 2017 - journals.lww.com
Objectives: Impaired oxygen delivery due to reduced cerebral blood flow is the hallmark of
delayed cerebral ischemia following subarachnoid hemorrhage. Since anemia reduces …

Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage

R Dhar, AR Zazulia, TO Videen, GJ Zipfel, CP Derdeyn… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Anemia is common after subarachnoid hemorrhage and may
exacerbate the reduction in oxygen delivery (DO2) underlying delayed cerebral ischemia …

The effect of packed red blood cell transfusion on cerebral oxygenation and metabolism after subarachnoid hemorrhage

P Kurtz, R Helbok, J Claassen, JM Schmidt… - Neurocritical care, 2016 - Springer
Background Anemia adversely affects cerebral oxygenation and metabolism after
subarachnoid hemorrhage (SAH) and is also associated with poor outcome. There is limited …

Packed red blood cell transfusion and decreased mortality in intracerebral hemorrhage

KN Sheth, AJ Gilson, Y Chang, MA Kumar… - …, 2011 - journals.lww.com
BACKGROUND: Accumulating data suggest that anemia worsens outcomes in critically ill
patients, including those with subarachnoid and intracerebral hemorrhage (ICH). Although …

Factors associated with brain tissue oxygenation changes after RBC transfusion in acute brain injury patients

EG Bogossian, V Rass, A Lindner… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: Anemia is common after acute brain injury and can be associated with brain
tissue hypoxia. RBC transfusion (RBCT) can improve brain oxygenation; however …

Comparison of induced hypertension, fluid bolus, and blood transfusion to augment cerebral oxygen delivery after subarachnoid hemorrhage

R Dhar, MT Scalfani, AR Zazulia, TO Videen… - Journal of …, 2012 - thejns.org
Object Critical reductions in oxygen delivery (DO 2) underlie the development of delayed
cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). If DO 2 is not promptly …

TRansfusion strategies in Acute brain INjured patients (TRAIN): a prospective multicenter randomized interventional trial protocol

FS Taccone, R Badenes, CB Rynkowski, P Bouzat… - Trials, 2023 - Springer
Background Although blood transfusions can be lifesaving in severe hemorrhage, they can
also have potential complications. As anemia has also been associated with poor outcomes …

Packed red blood cell transfusion increases local cerebral oxygenation

MJ Smith, MF Stiefel, S Magge, S Frangos… - Critical care …, 2005 - journals.lww.com
Objective: To determine a) whether packed red blood cell transfusion (RBCT) increases
local brain tissue oxygen partial pressure (Pbto 2) in a neurocritical care population; and b) …

The effect of red blood cell transfusion on cerebral oxygenation and metabolism after severe traumatic brain injury

DA Zygun, J Nortje, PJ Hutchinson, I Timofeev… - Critical care …, 2009 - journals.lww.com
Objective: There is evidence to suggest that anemia after severe traumatic brain injury (sTBI)
is detrimental. However, there is a paucity of evidence supporting the use of transfusion of …

Optimal hemoglobin concentration in patients with subarachnoid hemorrhage, acute ischemic stroke and traumatic brain injury

SR Leal-Noval, M Múñoz-Gómez… - Current opinion in …, 2008 - journals.lww.com
Both severe anemia and red blood-cell transfusion may negatively influence clinical
outcome in neurocritical patients. Acceptance of low hemoglobin concentrations may be …