Use of sequential quadrupling dose regimens to study efficacy of inhaled corticosteroids in asthma

K Phillips, J Oborne, TW Harrison, AE Tattersfield - Thorax, 2004 - thorax.bmj.com
Background: Inhaled corticosteroids are widely used to treat asthma. There is a need to be
able to compare different inhaled corticosteroids and different doses of an inhaled …

Methodological aspects on clinical trials with inhaled corticosteroids: results of two comparisons between two steroid aerosols in patients with asthma.

J Björkander, H Formgren, SA Johansson… - European Journal of …, 1982 - europepmc.org
The efficacy of beclomethasone dipropionate aerosol (BDA) 100 micrograms qid was
compared with that of budesonide aerosol 10 micrograms qid in 17 patients. The efficacy of …

Safety of oral corticosteroids.

M Weinberger - European journal of respiratory diseases …, 1982 - europepmc.org
Oral corticosteroids may be life-saving for symptoms of acute asthma, and short courses are
often useful to relieve even less serious acute exacerbations when the patient has become …

Endocrine effects of inhaled corticosteroids in children

CR Kapadia, TD Nebesio, SE Myers, S Willi… - JAMA …, 2016 - jamanetwork.com
Inhaled corticosteroids (ICSs) are widely used as first-line treatment for various chronic
respiratory illnesses. Advances in devices and formulations have reduced their local …

[引用][C] The place of high-dose inhaled corticosteroids in asthma therapy

MJ Smith - Drugs, 1987 - Springer
Inhaled corticosteroid therapy is well established as an effective form of maintenance
treatment in asthma and in conventional dosage has the advantage of avoiding the systemic …

Systemic bioavailability and potency of high-dose inhaled corticosteroids: a comparison of four inhaler devices and three drugs in healthy adult volunteers

D Wales, H Makker, J Kane, P Mc Dowell… - Chest, 1999 - Elsevier
Objectives To compare the systemic bioavailability (assessed by cortisol suppression) of
high-dose budesonide when given by four inhaler devices and orally. Also studied are the …

Controversies involving inhaled β-agonists and inhaled corticosteroids in the treatment of asthma

JV Fahy, HA Boushey - Clinics in chest medicine, 1995 - Elsevier
Controversy over the use of inhaled β-ago-nists has dated almost from their introduction as a
treatment for asthma. Their effectiveness as bronchodilators is not disputed, but there is …

Safety of inhaled corticosteroids for treating chronic obstructive pulmonary disease

MG Matera, V Cardaci, M Cazzola… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The frequent use of inhaled corticosteroids (ICSs), especially at higher doses,
has been accompanied by concern about both systemic and local side effects. Patients …

Inhaled corticosteroids in children: is there a 'safe'dosage?

AL Boner, GL Piacentini - Drug safety, 1993 - Springer
Inhaled corticosteroids are effective for the treatment of asthma. Because of the appreciation
of the importance of airway inflammation in the pathogenesis of the disease, these drugs are …

Impact of inhaled and intranasal corticosteroids on the growth of children

OD Wolthers - BioDrugs, 2000 - Springer
Since inhaled and intranasal corticosteroids may be systemically bioavailable, risk of growth
suppression cannot be ruled out in children treated with these compounds. The mechanisms …