Behavioral evaluations in developmental toxicity testing: MARTA survey results

EA Lochry, C Johnson, PJ Wier - Neurotoxicology and teratology, 1994 - Elsevier
Abstract During 1991, the Middle Atlantic Reproduction and Teratology Association
(MARTA) conducted a survey of laboratories performing behavioral evaluations as part of …

What it takes to validate behavioral toxicology tests: a belated commentary on the Collaborative Behavioral Teratology Study

A Weissman - Neurotoxicology and teratology, 1990 - Elsevier
“Design Considerations in Screening for Behavioral Teratogens: Results of the
Collaborative Behavioral Teratology Study”(CBTS) was an important conference whose …

Workshop on the qualitative and quantitative comparability of human and animal developmental neurotoxicity: Summary and implications

EZ Francis, CA Kimmel, DC Rees - Neurotoxicology and teratology, 1990 - Elsevier
Abstract The Workshop on the Qualitative and Quantitative Comparability of Human and
Animal Developmental Neurotoxicity was convened by the US Environmental Protection …

Current topics in postnatal behavioral testing

JW Henck, I Elayan, C Vorhees… - International …, 2016 - journals.sagepub.com
The study of developmental neurotoxicity (DNT) continues to be an important component of
safety evaluation of candidate therapeutic agents and of industrial and environmental …

Behavioral indices of neurotoxicity: what can be measured?

HA Tilson - Neurotoxicology and teratology, 1987 - Elsevier
The ability to identify and characterize the potential neurotoxicity of chemicals is an
important and necessary function of various regulatory agencies. Behavioral assessments of …

Behavioral test methods workshop

W Slikker Jr, K Acuff, WK Boyes, J Chelonis… - Neurotoxicology and …, 2005 - Elsevier
A one and a half day workshop on behavioral testing was conducted in order to discuss
experimental procedures and practices that may help enhance the utility of behavioral data …

Regulatory developmental neurotoxicity and human risk assessment.

EZ Francis - Neurotoxicology, 1992 - europepmc.org
A number of efforts, in the last 15 years, have been directed at developing protocols to
assess the potential developmental neurotoxicity (DN) of test agents. Japan and the United …

A better approach to in vivo developmental neurotoxicity assessment: alignment of rodent testing with effects seen in children after neurotoxic exposures

CV Vorhees, JN Sprowles, SL Regan… - Toxicology and applied …, 2018 - Elsevier
High throughput screens for developmental neurotoxicity (DN) will facilitate evaluation of
chemicals and can be used to prioritize those designated for follow-up. DN is evaluated …

Implementation of a primary screen for development neurotoxicity

PJ Wier, FJ Guerriero, RF Walker - Fundamental and Applied Toxicology, 1989 - Elsevier
A battery of tests to evaluate physical growth/development and neurobehavioral function
was conducted with 78 litters of control Sprague-Dawley rats given purified water by …

Scientific and regulatory issues relevant to assessing risk for developmental neurotoxicity: an overview

DC Rees, EZ Francis, CA Kimmel - Neurotoxicology and teratology, 1990 - Elsevier
The effects of chemical exposure on the developing nervous system have been documented
in both humans and animals for a variety of agents. However, the comparability of these …