Sepsis remains a major cause of morbidity and mortality worldwide, with increased burden
in low-and middle-resource settings. The role of the inflammatory response in the …

Sepsis has become a major health economic issue, with more patients dying in hospitals
due to sepsis related complications compared to breast and colorectal cancer together …

Sepsis, a life threating syndrome characterized by organ failure after infection, is the most
common cause of death in hospitalized patients. The treatment of sepsis is generally …

There has been a significant evolution in the definition and management of sepsis over the
last three decades. This is driven in part due to the advances made in our understanding of …

Sepsis is a host immune disorder induced by infection. It can lead to multiple organ
dysfunction syndrome (MODS), which has high morbidity and mortality. There has been …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. 1 These dysregulated host responses underpin the clinical …

Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Septic syndromes represent a major although largely underrecognized healthcare problem
worldwide, accounting for thousands of deaths every year. It is now agreed that sepsis …

The last two to three years provided several “big steps” regarding our understanding and
management of sepsis. The increasing insight into pathomechanisms of post-infectious …

Sepsis represents a life-threatening organ dysfunction due to an aberrant host response. Of
note is that majority of patients have experienced a severe immune depression during and …