Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century
M Manto, D Marmolino - The Cerebellum, 2009 - Springer
Cerebellar ataxias represent a group of disabling neurological disorders. Our understanding
of the pathogenesis of cerebellar ataxias is continuously expanding. A considerable number …
of the pathogenesis of cerebellar ataxias is continuously expanding. A considerable number …
Past, present and future therapeutics for cerebellar ataxias
D Marmolino, M Manto - Current neuropharmacology, 2010 - ingentaconnect.com
Cerebellar ataxias are a group of disabling neurological disorders. Patients exhibit a
cerebellar syndrome and can also present with extra-cerebellar deficits, namely pigmentary …
cerebellar syndrome and can also present with extra-cerebellar deficits, namely pigmentary …
Consensus paper: strengths and weaknesses of animal models of spinocerebellar ataxias and their clinical implications
J Cendelin, M Cvetanovic, M Gandelman, H Hirai… - The Cerebellum, 2022 - Springer
Spinocerebellar ataxias (SCAs) represent a large group of hereditary degenerative diseases
of the nervous system, in particular the cerebellum, and other systems that manifest with a …
of the nervous system, in particular the cerebellum, and other systems that manifest with a …
Cerebellar ataxias
M Manto, D Marmolino - Current opinion in neurology, 2009 - journals.lww.com
Cerebellar ataxias : Current Opinion in Neurology Cerebellar ataxias : Current Opinion in
Neurology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …
Neurology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …
Mutant mice as a model for cerebellar ataxia
U Grüsser-Cornehls, J Bäurle - Progress in neurobiology, 2001 - Elsevier
Not later than two synapses after their arrival in the cerebellar cortex all excitatory afferent
signals are subsequently transformed into inhibitory ones. Guaranteed by the exceedingly …
signals are subsequently transformed into inhibitory ones. Guaranteed by the exceedingly …
Advances in cerebellar disorders: pre-clinical models, therapeutic targets, and challenges
ABSTRACT Introduction Cerebellar ataxias (CAs) represent neurological disorders with
multiple etiologies and a high phenotypic variability. Despite progress in the understanding …
multiple etiologies and a high phenotypic variability. Despite progress in the understanding …
Cerebellar ataxias: an update
Cerebellar ataxias require a multidisciplinary approach for diagnosis and management. The
demonstration of anatomical relationships between the cerebellum and basal ganglia …
demonstration of anatomical relationships between the cerebellum and basal ganglia …
Cerebellar ataxia
SL Perlman - Current treatment options in neurology, 2000 - Springer
Opinion statement There is nothing more discouraging than for a patient to be given a
specific diagnosis, then to be told that there is nothing that can be done. Physicians are …
specific diagnosis, then to be told that there is nothing that can be done. Physicians are …
Epidemiology of inherited cerebellar ataxias and challenges in clinical research
F Pilotto, S Saxena - Clinical and translational neuroscience, 2018 - journals.sagepub.com
Cerebellar ataxia is a clinically heterogeneous group of disorders, which includes several
well-characterized genetic diseases as well as sporadic ataxias. The pathophysiology of …
well-characterized genetic diseases as well as sporadic ataxias. The pathophysiology of …
Cerebellar disorders—at the crossroad of molecular pathways and diagnosis
M Manto, D Marmolino - The Cerebellum, 2009 - Springer
Our understanding of the pathogenesis of cerebellar ataxias has started several decades
ago and is continuously growing. The numerous mechanisms of cerebellar dysfunction are …
ago and is continuously growing. The numerous mechanisms of cerebellar dysfunction are …