[HTML][HTML] Impact of aging on viral infections
J Leng, DR Goldstein - Microbes and infection, 2010 - Elsevier
Older people are more susceptible to a variety of viral infections, including those that induce
respiratory disease, resulting in higher morbidity and mortality than younger people. Aging …
respiratory disease, resulting in higher morbidity and mortality than younger people. Aging …
Role of aging on innate responses to viral infections
DR Goldstein - Journals of Gerontology Series A: Biomedical …, 2012 - academic.oup.com
Older people exhibit increased morbidity and mortality after viral infections than younger
people. Additionally, vaccines are less protective in older people than in younger people. As …
people. Additionally, vaccines are less protective in older people than in younger people. As …
[HTML][HTML] Aging and options to halt declining immunity to virus infections
MÁ Palacios-Pedrero, ADME Osterhaus… - Frontiers in …, 2021 - frontiersin.org
Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …
[HTML][HTML] Aging of the immune system: research challenges to enhance the health span of older adults
L Haynes - Frontiers in aging, 2020 - frontiersin.org
The world's population is aging, which brings about huge scientific challenges. Since the
biological process of aging is by far the greatest risk factor for most chronic diseases …
biological process of aging is by far the greatest risk factor for most chronic diseases …
Persistent viral infections and immune aging
S Brunner, D Herndler-Brandstetter, B Weinberger… - Ageing research …, 2011 - Elsevier
Immunosenescence comprises a set of dynamic changes occurring to both, the innate as
well as the adaptive immune system that accompany human aging and result in complex …
well as the adaptive immune system that accompany human aging and result in complex …
Effects of aging on the adaptive immune response to respiratory virus infections
Severe acute respiratory disease caused by respiratory virus infections in individuals aged
65 years and older and in high-risk adults, such as those with chronic cardiopulmonary …
65 years and older and in high-risk adults, such as those with chronic cardiopulmonary …
Understanding immunosenescence and its impact on vaccination of older adults
JC Allen, FR Toapanta, W Chen, SM Tennant - Vaccine, 2020 - Elsevier
Older adults are more susceptible to viral and bacterial infection, and experience higher
incidence and severity of infectious diseases. Although vaccination is the most logical …
incidence and severity of infectious diseases. Although vaccination is the most logical …
Ageing and respiratory infections: the airway of ageing
K Haq, JE McElhaney - Immunology letters, 2014 - Elsevier
Respiratory infections are a leading cause of infectious disease burden worldwide
especially among the elderly. Furthermore, a direct relationship between ageing and …
especially among the elderly. Furthermore, a direct relationship between ageing and …
Innate immune responses in the ageing lung
DM Boe, LA Boule, EJ Kovacs - Clinical & Experimental …, 2017 - academic.oup.com
The world is undergoing an unprecedented shift in demographics, with the number of
individuals over the age of 60 years projected to reach 2 billion or more by 2050 …
individuals over the age of 60 years projected to reach 2 billion or more by 2050 …
[HTML][HTML] Ineffective humoral immunity in the elderly
KS McGlauchlen, LA Vogel - Microbes and infection, 2003 - Elsevier
As individuals age, dysfunction of the immune system leads to an increased incidence of
infectious disease. Due to the complex network of cellular interactions and the multi-factorial …
infectious disease. Due to the complex network of cellular interactions and the multi-factorial …