[HTML][HTML] Electrophysiological mechanisms of Brugada syndrome: insights from pre-clinical and clinical studies

G Tse, T Liu, KHC Li, V Laxton, YWF Chan… - Frontiers in …, 2016 - frontiersin.org
Brugada syndrome (BrS), is a primary electrical disorder predisposing affected individuals to
sudden cardiac death via the development of ventricular tachycardia and fibrillation (VT/VF) …

[HTML][HTML] Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies

KHC Li, S Lee, C Yin, T Liu, T Ngarmukos, G Conte… - IJC Heart & …, 2020 - Elsevier
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

[HTML][HTML] Genetic and molecular mechanisms in brugada syndrome

E Moras, K Gandhi, B Narasimhan, R Brugada… - Cells, 2023 - mdpi.com
Brugada syndrome is a rare hereditary arrhythmia disorder characterized by a distinctive
electrocardiogram pattern and an elevated risk of ventricular arrhythmias and sudden …

Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?

PG Meregalli, AAM Wilde, HL Tan - Cardiovascular research, 2005 - academic.oup.com
After its recognition as a distinct clinical entity, Brugada syndrome is increasingly recognized
worldwide as an important cause of sudden cardiac death. Brugada syndrome exhibits …

The Brugada Syndrome− An Update−

W Shimizu - Internal medicine, 2005 - jstage.jst.go.jp
Brugada syndrome is characterized by ST-segment elevation in the right precordial leads
(V1–V3) and an episode of ventricular fibrillation (VF) in the absence of structural heart …

Clinical aspects and physiopathology of Brugada syndrome: review of current concepts

E Herbert, M Chahine - Canadian journal of physiology and …, 2006 - cdnsciencepub.com
Brugada syndrome (BS) is an inherited cardiac disorder characterized by typical
electrocardiographic patterns of ST segment elevation in the precordial leads, right bundle …

[HTML][HTML] Distinct functional defect of three novel Brugada syndrome related cardiac sodium channel mutations

CH Hsueh, WP Chen, JL Lin, CT Tsai, YB Liu… - Journal of Biomedical …, 2009 - Springer
The Brugada syndrome is characterized by ST segment elevation in the right precodial
leads V1-V3 on surface ECG accompanied by episodes of ventricular fibrillation causing …

Complex genetic background in a large family with Brugada syndrome

S Saber, MY Amarouch, AF Fazelifar… - Physiological …, 2015 - Wiley Online Library
Abstract The Brugada syndrome (BrS) is an inherited arrhythmia characterized by ST‐
segment elevation in V1–V3 leads and negative T wave on standard ECG. BrS patients are …

[HTML][HTML] Brugada syndrome: from molecular mechanisms and genetics to risk stratification

IP Popa, DN Șerban, MA Mărănducă… - International Journal of …, 2023 - mdpi.com
Brugada syndrome (BrS) is a rare hereditary arrhythmia disorder, with a distinctive ECG
pattern, correlated with an increased risk of ventricular arrhythmias and sudden cardiac …

[HTML][HTML] Brugada Syndrome: In search of a cause

D Corrado, F Migliore, A Zorzi - Journal of the American College of …, 2018 - jacc.org
classified as an inherited channelopathy and has been linked to mutations in the SCN5A
gene that encodes the alpha subunit of the cardiac sodium channel (1). Patients with BrS …