As a step towards better integrating protein three-dimensional (3D) structural information in
cancer systems biology, the Northeast Structural Genomics Consortium (NESG)(www. nesg …

A 2860-bp cDNA was isolated from a human fetal brain cDNA library by high throughput
cDNA sequencing, which encodes a putative protein with 186 amino acids. The putative …

The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …

Structural genomics provides an important approach for characterizing and understanding
systems biology. As a step toward better integrating protein three-dimensional (3D) …

Using a NotI linking clone NR-025 as a probe, we isolated a novel putative member of the
RB binding protein family, namely a human retinoblastoma binding protein 2 homologue …

We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …

Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …

Human retinoblastoma binding protein 9 (RBBP9) is an interacting partner of the
retinoblastoma susceptibility protein (Rb). RBBP9 is a tumor-associated protein required for …

RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and
essential for embryonic development. Furthermore, RBBP6 is a critical element in …

In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of
retinoblastoma protein (pRb)-activity. Members of the previously described family of …