Revised Manuscript Received July 7, 1994® abstract: Cecropin B2 (CecB) is a 35 amino
acid residue, antibacterial peptide that was isolated from the hemolymph and cuticular …

RB Merrifield,* LD Vizioli, and HG Boman abstract: Cecropin A (l-33) was synthesized by an
improved stepwise solid-phase method. The synthesis was designed to give high coupling …

Revised Manuscript Received June 29, 1995® abstract: Cecropins are positively charged
antibacterial polypeptides that were originally isolated from insects. Later on a mammalian …

Cecropin D was synthesized by solid-phase methods and shown to be homogeneous and of
correct composition and molecular weight. It was indistinguishable from natural cecropin D …

Cecropin A is a naturally occurring peptide with bactericidal activity against gram-negative
and gram-positive bacteria. Production of large quantities of bactericidal peptides that are …

Six analogues of the 37-residue antibacterial peptide cecropin A were synthesized by the
solid-phase method: cecropin A-(2-37),[Glu2] cecropin A,[Pro4] cecropin A,[Glu6] cecropin …

The lytic peptides, cecropins, were originally isolated from the haemolymph of the giant silk
moth, Hyalophora cecropia and possess antibacterial and anticancer activity in vitro. This …

The existence of an inducible humoral immune system in insects has been long known
(review [11). Apart from the presence of lysozyme activity the molecular basis for the killing …

The insect humoral defense system produces antibacterial peptides called cecropins.
Cecropins were initially isolated from Hyalophora cecropia pupae and have since been …

Revised Manuscript Received March 24, 19949 abstract: The binding and state of
aggregation of cecropin in large unilamellar vesicles of different surface potential and …