Mimosine [β‐[N‐(3‐hydroxy‐4‐oxypyridyl)]‐α‐aminopropionic acid] is a non‐protein amino
acid found in the members of Mimosoideae family. There are a considerable number of …

Matrine has shown therapeutic and/or adjuvant therapeutic effects on the treatment of some
patients with breast cancer. However, its mechanisms of action are largely unknown. To …

Matrine is a quinazoline alkaloid extracted from Sophora flavescens. The aim of the present
study was to determine whether matrine can induce autophagy in the human HeLa and …

Abstract Five matrine-type alkaloids (1‒5) including two new compounds (1 and 3) and a
new natural product (2) were isolated from the roots of Sophora tonkinesis. Their structures …

抄録 Matrine, having an anti-tumor effect, a main constituent of Sophora flavescents Ait, was
found to differentiate and morphologically change K562 cells at O. 1mg/ml to polychromatic …

Although matrine, a primary active component of dried Sophora flavescens root (ku shen), is
known to induce apoptosis in a variety of tumor cells in vitro, the molecular mechanism of …

Non-small cell lung carcinoma (NSCLC) is one of the most refractory cancers in the clinic; it
is insensitive to chemotherapy and is usually excised. However, screening natural …

Matrine is a widely used Chinese herbal medicine that has historically been used in the
treatment of inflammation and cancer. However, the antimetastatic effects and associated …

Major progress has been made in cancer research; however, cancer remains one of the
most important health-related burdens. Sericulture importance is no longer limited to the …

Four new alkaloids (1–4) belonging to rare examples of bis-amide matrine-type were
isolated from the seeds of sophora alopecuroides. Their structures including absolute …