Adipogenesis: a cross-talk between cell proliferation and cell differentiation

L Fajas - Annals of medicine, 2003 - Taylor & Francis
The transition between cell proliferation and cell differentiation taking place during adipocyte
differentiation is a tightly regulated process where both cell cycle regulators and …

[HTML][HTML] Adipose tissue plasticity from WAT to BAT and in between

YH Lee, EP Mottillo, JG Granneman - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Adipose tissue plays an essential role in regulating energy balance through its metabolic,
cellular and endocrine functions. Adipose tissue has been historically classified into …

The developmental origins of adipose tissue

DC Berry, D Stenesen, D Zeve, JM Graff - Development, 2013 - journals.biologists.com
Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms.
Once formed, the tissue is dynamic, responding to homeostatic and external cues and …

Improved methodologies for the study of adipose biology: insights gained and opportunities ahead

QA Wang, PE Scherer, RK Gupta - Journal of lipid research, 2014 - ASBMB
Adipocyte differentiation and function have become areas of intense focus in the field of
energy metabolism; however, understanding the role of specific genes in the establishment …

Forming functional fat: a growing understanding of adipocyte differentiation

AG Cristancho, MA Lazar - Nature reviews Molecular cell biology, 2011 - nature.com
Adipose tissue, which is primarily composed of adipocytes, is crucial for maintaining energy
and metabolic homeostasis. Adipogenesis is thought to occur in two stages: commitment of …

Molecular mechanisms of adipocyte differentiation

Q Tong, GS Hotamisligil - Reviews in endocrine and metabolic disorders, 2001 - Springer
Adipose tissue plays an important role in energy homeostasis. In mammals, the two distinct
types of adipose tissue function at opposite sides of the energy balance equation. White …

Peroxisome proliferator-activated receptor gamma and the control of adipogenesis

RP Brun, JB Kim, E Hu… - Current Opinion in …, 1997 - journals.lww.com
The adipose cell is now known to play a complex role in energy homeostasis, storing energy
and signaling to other tissues concerning the state of energy balance. The past several …

Transcriptional targets in adipocyte biology

E Rosen, J Eguchi, Z Xu - Expert opinion on therapeutic targets, 2009 - Taylor & Francis
The global burden of metabolic disease demands that we develop new therapeutic
strategies. Many of these approaches may center on manipulating the behavior of …

Molecular regulation of adipogenesis

ED Rosen, BM Spiegelman - Annual review of cell and …, 2000 - annualreviews.org
▪ Abstract Adipogenesis, or the development of fat cells from preadipocytes, has been one of
the most intensely studied models of cellular differentiation. In part this has been because of …

Adipose tissue: an endocrine organ playing a role in metabolic regulation

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2016 - degruyter.com
Adipose tissue is a complex endocrine organ with an intricate role in whole body
homeostasis. Beyond storing energy, adipose tissue is fundamental in numerous processes …