Potential therapeutics against neurological disorders: Natural products-based drugs

A Rauf, MM Rahman - Frontiers in Pharmacology, 2022 - frontiersin.org
Neurodegenerative disorders, which are defined by the breakdown of neurons over time,
are affecting an increasing number of people. Stroke, Alzheimer's, Parkinson's, Multiple …

Indole-containing natural products 2019–2022: isolations, reappraisals, syntheses, and biological activities

SM Umer, M Solangi, KM Khan, RSZ Saleem - Molecules, 2022 - mdpi.com
Indole alkaloids represent a large subset of natural products, with more than 4100 known
compounds. The majority of these alkaloids are biologically active, with some exhibiting …

Herbal medicine for psychiatric disorders: Psychopharmacology and neuroscience-based nomenclature

SW Tang, WH Tang, BE Leonard - The World Journal of Biological …, 2019 - Taylor & Francis
Objectives: Herbs are frequently and concurrently used with prescribed drugs by patients
worldwide. While clinical trials have found some herbs to be as useful as standard …

Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications

S Fernández, V Arnáiz, D Rufo, Y Arroyo - Marine Drugs, 2024 - mdpi.com
Indole is a versatile pharmacophore widely distributed in bioactive natural products. This
privileged scaffold has been found in a variety of molecules isolated from marine organisms …

Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence

J Sarris, E McIntyre, DA Camfield - CNS drugs, 2013 - Springer
Research in the area of herbal psychopharmacology has revealed a variety of promising
medicines that may provide benefit in the treatment of general anxiety and specific anxiety …

Alkaloids from apocynaceae: origin, pharmacotherapeutic properties, and structure-activity studies

A Dey, A Mukherjee, M Chaudhury - Studies in Natural Products Chemistry, 2017 - Elsevier
Alkaloids are a diverse group of naturally occurring secondary compounds derived from
amino acids or the process of transamination. Some synthetic compounds with similar …

Medicinal plants and dietary supplements: Sources for innovative treatments or adjuncts?

J Cott - Psychopharmacology Bulletin, 1995 - psycnet.apa.org
Discusses advances made in natural products research and its implications for
psychopharmacology. Pharmacology began with attempts to understand the biological …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

M Somei, F Yamada - Natural product reports, 2004 - pubs.rsc.org
Covering: January to December 2002. Previous review: Nat. Prod. Rep., 2003, 20, 171This
review covers simple indole alkaloids and those with a nonrearranged monoterpenoid unit …

New therapeutic potential for psychoactive natural products

KM Prevatt-Smith, TE Prisinzano - Natural product reports, 2010 - pubs.rsc.org
Much of our knowledge in neuroscience was discovered through the study of mind-altering
natural products. However, although much has been learned about human physiology and …

Nine traditional Chinese herbal formulas for the treatment of depression: an ethnopharmacology, phytochemistry, and pharmacology review

D Feng, T Tang, X Lin, Z Yang, S Yang… - Neuropsychiatric …, 2016 - Taylor & Francis
Depression is a major mental disorder, and is currently recognized as the second-leading
cause of disability worldwide. However, the therapeutic effect of antidepressants remains …