Gerald A. Meininger, University of Missouri, USA complications. Chantler and Lakatta (2012)
elegantly describe the concept of arterial ventricular coupling and provide valuable …

This review summarizes a presentation given during the “Countermeasures to
Cardiovascular Aging Symposium” that was part of the American Physiological Society …

Aging is associated with structural and functional changes in the vasculature, including
endothelial dysfunction, arterial stiffening and remodeling, impaired angiogenesis, and …

Large elastic arterial stiffening and endothelial dysfunction are phenotypic characteristics of
vascular aging, a major risk factor for age-associated cardiovascular diseases. Compared to …

Vascular aging, characterized by endothelial dysfunction and large elastic arterial stiffening,
is a major risk factor for age-associated cardiovascular disease (CVD). Although women …

New Findings What is the topic of this review? This brief review discusses potential sex
differences in arterial function across the age span, with special emphasis on the effects of …

Aging is the major risk factor per se for the development of cardiovascular diseases. The
senescence of the endothelial cells (ECs) that line the lumen of blood vessels is the cellular …

The incidence and prevalence of cardiovascular disease is highest among the elderly, in
part, due to deleterious effects of advancing age on the heart and blood vessels. Aging, a …

Advancing age may be the most potent independent predictor of future cardiovascular
events, a relationship that is not fully explained by time‐related changes in traditional …

Vascular endothelial dysfunction is regarded as a primary phenotypic expression of normal
human aging. This senescence-induced disorder is the likely culprit underlying the …