Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement

S Warnakulasuriya, J Reibel, J Bouquot… - Journal of oral …, 2008 - Wiley Online Library
At a workshop coordinated by the WHO Collaborating Centre for Oral Cancer and Precancer
in the United Kingdom issues related to potentially malignant disorders of the oral cavity …

Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation

O Kujan, RJ Oliver, A Khattab, SA Roberts, N Thakker… - Oral oncology, 2006 - Elsevier
The aim of this paper is to assess the reproducibility of a novel binary grading system
(high/low risk) of oral epithelial dysplasia and to compare it with the WHO classification …

Why oral histopathology suffers inter-observer variability on grading oral epithelial dysplasia: an attempt to understand the sources of variation

O Kujan, A Khattab, RJ Oliver, SA Roberts, N Thakker… - Oral oncology, 2007 - Elsevier
The present study attempted to assess the reasons behind the inter-observer variation in
grading oral epithelial dysplasia (OED). Three oral pathologists and one general pathologist …

Observer agreement in the grading of oral epithelial dysplasia

B D. J, L D. W, LI, J RC K, L J. L - Community dentistry and oral …, 2003 - Wiley Online Library
Objectives: To determine the extent of observer agreement in diagnosis of oral epithelial
dysplasia (OED). Published studies of OED examiner agreement report relatively low …

[HTML][HTML] Malignant transformation of oral epithelial dysplasia: a real-world evaluation of histopathologic grading

F Dost, K Lê Cao, PJ Ford, C Ades, CS Farah - Oral surgery, oral medicine …, 2014 - Elsevier
Objective This study describes the predictive value of oral epithelial dysplasia (OED)
grading as an indicator for malignant transformation and progression. Study Design The …

[HTML][HTML] Oral epithelial dysplasia: Classifications and clinical relevance in risk assessment of oral potentially malignant disorders

K Ranganathan, L Kavitha - Journal of Oral and Maxillofacial …, 2019 - journals.lww.com
After more than a decade, the World Health Organization (WHO) published the revised
grading system for oral epithelial dysplasia in 2017. The revised classification has changes …

Oral epithelial dysplasia: Causes, quantification, prognosis, and management challenges

WM Tilakaratne, PR Jayasooriya… - Periodontology …, 2019 - Wiley Online Library
Oral epithelial dysplasia is a spectrum of architectural and cytological epithelial changes
caused by accumulation of genetic changes, and is associated with an increased risk of …

Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials

PM Speight, TJ Abram, PN Floriano, R James… - Oral surgery, oral …, 2015 - Elsevier
Objective Interobserver agreement in the context of oral epithelial dysplasia (OED) grading
has been notoriously unreliable and can impose barriers for developing new molecular …

Epithelial dysplasia of the oral mucosa—Diagnostic problems and prognostic features

JE Bouquot, PM Speight, PM Farthing - Current Diagnostic Pathology, 2006 - Elsevier
Many oral cancers are preceded by potentially malignant lesions, which may appear as
white or red patches on the oral mucosa. In the absence of validated molecular markers, the …

The binary oral dysplasia grading system: validity testing and suggested improvement

P Nankivell, H Williams, P Matthews… - Oral surgery, oral …, 2013 - Elsevier
OBJECTIVES: A binary system is reputed to be superior to the World Health Organization
(WHO) system in grading oral dysplasia. We aimed to validate its reproducibility and …