Chondroitin sulfate (CS) is the placental receptor for the VAR2CSA malaria protein,
expressed at the surface of infected erythrocytes during Plasmodium falciparum infection …

Placental malaria infection is mediated by the binding of the malarial VAR2CSA protein to
the placental glycosaminoglycan, chondroitin sulfate. Recombinant subfragments of …

Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to
be shared between placental trophoblasts and cancer cells and can be detected by the …

Placental malaria, a serious infection caused by the parasite Plasmodium falciparum, is
characterized by the selective accumulation of infected erythrocytes (IEs) in the placentas of …

Placental malaria is a serious problem in sub-Saharan Africa. Young women are particular
susceptible to contracting this form of malaria during their first or second pregnancy despite …

Plasmodium falciparum engineer infected erythrocytes to present the malarial protein,
VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively expressed in the …

Malaria is a major global health problem. Pregnant women are susceptible to infection
regardless of previously acquired immunity. Placental malaria is caused by parasites …

During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the
placenta, causing health problems for both the mother and fetus. The specific adherence is …

Malaria remains a major threat, in sub-Saharan Africa primarily, and the most deadly
infections are those with Plasmodium falciparum. Pregnancy-associated malaria is a …

Background Pregnancy malaria is caused by Plasmodium falciparum-infected erythrocytes
binding the placental receptor chondroitin sulfate A (CSA). This results in accumulation of …