Multidrug resistance in tumor cells poses a major obstacle to efficient chemotherapy.
Several types of agents have been recognized as multidrug resistance inhibitors, among …

Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug
resistance reversal agents in cancer - ScienceDirect Skip to main contentSkip to article Elsevier …

A series of novel hybrids 10a–m were designed and synthesized by coupling phenylsulfonyl
furoxans with gemcitabine through various diols or alcohol amine linkers, and their …

Novel furoxan-based nitric oxide-releasing derivatives 6a–p of hydroxylcinnamic acids were
synthesized by coupling the carboxyl group of hydroxylcinnamic acids with furoxan through …

To search for novel nitric oxide (NO) releasing anti-tumor agents, a series of novel
furoxan/oridonin hybrids were designed and synthesized. Firstly, the nitrate/nitrite levels in …

A series of novel nitric oxide (NO)-releasing 5, 8-quinolinedione/furoxan hybrids (8a-h and
9a-h) were designed and synthesized through coupling different alkanolamine substituted …

A series of novel nitric oxide-donating sixalkoxyl biphenyl derivatives (14a–l) were
synthesized by coupling furoxan with alkoxyl biphenyl skeleton using amino acids as the …

Hybridization of nitric oxide (NO) donors with known anti-cancer agents have been emerged
as a strategy to achieve improved therapeutic effect and to overcome chemo-resistance in …

Sixteen furoxan-based nitric oxide (NO) releasing coumarin derivatives (6a–c, 8a–g, 10a,
13a, b, 15, and 17a, b) were designed, synthesized, and evaluated against the A549, HeLa …

Novel quinoline derivatives carrying nitrones and oxime as nitric oxide donors were
prepared and characterized using different spectroscopic techniques. Nitrones can release …