Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer

LR Motadi, KD Bhoola, Z Dlamini - Immunobiology, 2011 - Elsevier
Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …

Expression Analysis of RbBP6 in human cancers: a Prospective biomarker

Z Mbita, R Hull, M Mbele, T Makhafola… - Anti-Cancer …, 2019 - journals.lww.com
Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …

Overexpression of RBBP6, alone or combined with mutant TP53, is predictive of poor prognosis in colon cancer

J Chen, H Tang, Z Wu, C Zhou, T Jiang, Y Xue… - PloS one, 2013 - journals.plos.org
Retinoblastoma binding protein 6 (RBBP6) plays an important role in chaperone-mediated
ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic …

RBBP6 induces non-small cell lung cancer cell proliferation and high expression is associated with poor prognosis

QS Wang, SR Wei, HL Xiao - Oncology Letters, 2020 - spandidos-publications.com
Lung cancer is the most common cause of cancer-associated mortality in China with 85% of
patients having non-small cell lung cancer (NSCLC). Identifying NSCLC driver genes and …

Retinoblastoma binding protein 6, another p53 monitor

M Ntwasa - Trends in cancer, 2016 - cell.com
The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, is essential for
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …

De-regulation of the RBBP6 isoform 3/DWNN in human cancers

Z Mbita, M Meyer, A Skepu, M Hosie, J Rees… - Molecular and cellular …, 2012 - Springer
Abstract Retinoblastoma binding protein 6 (RBBP6) is a nuclear protein, previously
implicated in the regulation of cell cycle and apoptosis. The human RBBP6 gene codes for …

[HTML][HTML] High expression of retinoblastoma-binding protein 2 (RBP2) in patients with hepatocellular carcinoma and its prognostic significance

ZY Wang, J Yang, CK Liu, SQ Shen - Medical Science Monitor …, 2017 - ncbi.nlm.nih.gov
Background Recently, some studies have found that retinoblastoma-binding protein 2
(RBP2) is involved in the development and progression of many kinds of malignant tumors …

[HTML][HTML] RBBP6 promotes human cervical carcinoma malignancy via JNK signaling pathway

F Teng, HJ Ruan, J Xu, J Ni, B Qian, R Shen… - Biomedicine & …, 2018 - Elsevier
Previous studies have shown that retinoblastoma binding protein 6 (RBBP6) was
overexpressed in malignant tumors and was correlated with poorer prognosis in various …

Retinoblastoma binding protein 4 up-regulation is correlated with hepatic metastasis and poor prognosis in colon cancer patients

YD Li, Z Lv, HY Xie, SS Zheng - Hepatobiliary & Pancreatic Diseases …, 2019 - Elsevier
Background Retinoblastoma binding protein 4 (RBBP4) plays an essential role in the
development of multiple cancers. However, its relationship with prognosis in colon cancer …

Silencing RBBP6 (Retinoblastoma Binding Protein 6) sensitises breast cancer cells MCF7 to staurosporine and camptothecin-induced cell death

P Moela, MMS Choene, LR Motadi - Immunobiology, 2014 - Elsevier
Abstract Retinoblastoma Binding Protein 6 (RBBP6) is a multi-domain protein that uses its
ring finger domain to interact with p53 and pRb tumour suppressor genes. The mechanism …