Oral semaglutide in type 2 diabetes

SL Anderson, TR Beutel, JM Trujillo - Journal of Diabetes and its …, 2020 - Elsevier
Background Previously, the only available glucagon-like peptide-1 receptor agonists (GLP-1
RA) were injectable. Approval of oral semaglutide (Rybelsus®) represents the first orally …

Oral semaglutide: first-in-class oral GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus

K Cowart - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
Objective: The purpose of this article is to review the pharmacological characteristics and
clinical evidence of oral semaglutide for the treatment of type 2 diabetes mellitus (T2DM) …

Management of type 2 diabetes with oral semaglutide: Practical guidance for pharmacists

MP Kane, CL Triplitt… - American Journal of …, 2021 - academic.oup.com
Purpose To provide pharmacists with information on counseling patients with type 2
diabetes (T2D) receiving oral semaglutide. Summary Oral semaglutide, the first oral …

[HTML][HTML] The efficacy and safety of oral semaglutide for glycaemic management in adults with type 2 diabetes compared to subcutaneous semaglutide, placebo, and …

Y Alhindi, A Avery - Contemporary clinical trials communications, 2022 - Elsevier
Aim Semaglutide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA)
indicated for glycaemic management in adults with type 2 diabetes (T2D). Oral semaglutide …

Efficacy and safety of oral semaglutide in type 2 diabetes mellitus: a systematic review and meta-analysis

A Li, X Su, S Hu, Y Wang - Diabetes Research and Clinical Practice, 2023 - Elsevier
Objectives To investigate the efficacy and safety of oral semaglutide 7 and 14 mg, the only
orally delivered glucagon-like peptide-1 (GLP-1) receptor agonist tablet approved for type 2 …

Safety and pharmacokinetics of single and multiple ascending doses of the novel oral human GLP-1 analogue, oral semaglutide, in healthy subjects and subjects with …

C Granhall, M Donsmark, TM Blicher, G Golor… - Clinical …, 2019 - Springer
Background Oral semaglutide is a novel tablet containing the human glucagon-like peptide-
1 (GLP‑1) analogue semaglutide, co-formulated with the absorption enhancer sodium N-(8 …

Semaglutide for type 2 diabetes mellitus: a systematic review and meta‐analysis

P Andreadis, T Karagiannis, K Malandris… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aims To assess the efficacy and safety of semaglutide, a recently approved glucagon‐like
peptide 1 receptor agonist (GLP‐1 RA) for type 2 diabetes. Materials and methods We …

Oral semaglutide for the treatment of type 2 diabetes

MS Hedrington, SN Davis - Expert opinion on pharmacotherapy, 2019 - Taylor & Francis
ABSTRACT Introduction: Glucagon-like peptide-1 (GLP-1) receptor agonists are highly
potent antihyperglycemic drugs that impose low risk of hypoglycemia and also result in body …

Efficacy and safety of the glucagon-like peptide-1 receptor agonist oral semaglutide in patients with type 2 diabetes mellitus: a systematic review and meta-analysis

J Li, K He, J Ge, C Li, Z Jing - Diabetes research and clinical practice, 2021 - Elsevier
Objectives To evaluate the efficacy and safety of the glucagon-like peptide-1 (GLP-1)
receptor agonist (RA) oral semaglutide in the treatment of type 2 diabetes mellitus (T2DM) …

Efficacy of oral semaglutide: overview of the PIONEER clinical trial program and implications for managed care.

HW Rodbard, T Dougherty… - The American journal of …, 2020 - europepmc.org
The first tablet formulation of a glucagon-like peptide-1 receptor agonist (GLP-1RA), oral
semaglutide, was approved in September 2019 for the treatment of adults with type 2 …