[HTML][HTML] Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy

A Ahmet, H Kim, S Spier - Allergy, Asthma & Clinical Immunology, 2011 - Springer
Inhaled corticosteroids (ICSs) are the most effective anti-inflammatory agents available for
the treatment of asthma and represent the mainstay of therapy for most patients with the …

[HTML][HTML] Inhaled corticosteroids and secondary adrenal insufficiency

V Sannarangappa, R Jalleh - The open respiratory medicine …, 2014 - ncbi.nlm.nih.gov
Inhaled corticosteroids (ICS) have been used as first line treatment of asthma for many
decades. ICS are a form of exogenous glucocorticosteroids that can suppress the …

Moderate dose inhaled corticosteroid-induced symptomatic adrenal suppression: case report and review of the literature

RH Schwartz, O Neacsu, DP Ascher… - Clinical …, 2012 - journals.sagepub.com
Inhaled corticosteroids (ICS) are drugs of choice for persistent asthma. Less than 500 µg/d of
fluticasone are believed to be safe. We found 92 cases of adrenal suppression in PubMed; …

[HTML][HTML] CSACI position statement: systemic effect of inhaled corticosteroids on adrenal suppression in the management of pediatric asthma

K Issa-El-Khoury, H Kim, ES Chan… - Allergy, Asthma & …, 2015 - Springer
Asthma is a chronic inflammatory disease of the airways that affects a growing number of
children and adolescents. Inhaled corticosteroids (ICS) are the mainstay of treatment in …

Inhaled corticosteroids and adrenal insufficiency: prevalence and clinical presentation

M Molimard, PO Girodet, C Pollet, A Fourrier-Réglat… - Drug safety, 2008 - Springer
Objective: Adrenal insufficiency (AI) is a potentially life-threatening condition. It is known that
high doses of inhaled corticosteroids (ICS) can induce systemic adverse effects. Currently …

Inhaled glucocorticoids and adrenal function: an update

S Crowley - Paediatric Respiratory Reviews, 2003 - Elsevier
For the vast majority of asthmatic children, treatment with inhaled glucocorticoids is safe and
effective. Mild impairment of adrenal function of doubtful clinical significance is known to …

The use of inhaled corticosteroids and the risk of adrenal insufficiency

F Lapi, A Kezouh, S Suissa… - European Respiratory …, 2013 - Eur Respiratory Soc
Adrenal insufficiency is a potential complication of therapy with an inhaled corticosteroid
(ICS). Although prior studies found the highest risk of adrenal insufficiency with fluticasone, a …

Symptomatic adrenal insufficiency during inhaled corticosteroid treatment

L Patel, JK Wales, MS Kibirige… - Archives of disease in …, 2001 - adc.bmj.com
Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may
occur on withdrawal of corticosteroid treatment but has not previously been reported during …

Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom

GRG Todd, CL Acerini, R Ross-Russell… - Archives of Disease in …, 2002 - adc.bmj.com
Background: Until recently, only two cases of acute adrenal crisis associated with inhaled
corticosteroids (ICS) had been reported worldwide. We identified four additional cases and …

[HTML][HTML] Adrenal suppression from glucocorticoids: preventing an iatrogenic cause of morbidity and mortality in children

A Ahmet, A Mokashi, EB Goldbloom, C Huot… - BMJ paediatrics …, 2019 - ncbi.nlm.nih.gov
Adrenal suppression (AS) is an important side effect of glucocorticoids (GCs) including
inhaled corticosteroids (ICS). AS can often be asymptomatic or associated with non-specific …