Introduction: Current therapies for chronic obstructive pulmonary disease (COPD) focus on
the improvement of clinical symptoms via the use of bronchodilators: β2-adrenoreceptor …

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy document for the
treatment of chronic obstructive pulmonary disease (COPD) suggests that, after …

The current recommendations for the treatment of chronic obstructive pulmonary disease
(COPD) are pushing towards triple combination therapy based on the combination of an …

A growing body of evidence suggests that triple therapy with an antimuscarinic agent, a long-
acting β2-agonist, and an inhaled corticosteroid is efficacious in patients with more severe …

We systematically reviewed the current knowledge on fixed-dose triple therapies for the
treatment of chronic obstructive pulmonary disease (COPD), with a specific focus on its …

Highlights•Triple therapy in a single inhaler is a new therapeutic option for COPD.•Three
fixed dose combinations of inhaled corticosteroids LABA and LAMA are in Phase III of …

Introduction An incremental approach using open-triple therapy may improve outcomes in
patients with chronic obstructive pulmonary disease (COPD). However, there is little …

The pharmacological treatment of chronic obstructive pulmonary disease (COPD) focuses
on 2 main objectives: controlling symptoms (in the form of reduced symptoms, improved …

Introduction: Chronic obstructive pulmonary disease (COPD) is a complex respiratory
disorder, whose medical and socioeconomic burden as one of the main causes of morbidity …

New guidelines emphasize combination bronchodilators as a mainstay of therapy for many
patients with symptomatic COPD and there are several new combination bronchodilator …