Combating bacterial biofilms: current and emerging antibiofilm strategies for treating persistent infections
AG Abdelhamid, AE Yousef - Antibiotics, 2023 - mdpi.com
Biofilms are intricate multicellular structures created by microorganisms on living (biotic) or
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …
Strategies for combating antibiotic resistance in bacterial biofilms
KE Grooters, JC Ku, DM Richter, MJ Krinock… - Frontiers in Cellular …, 2024 - frontiersin.org
Biofilms, which are complexes of microorganisms that adhere to surfaces and secrete
protective extracellular matrices, wield substantial influence across diverse domains such as …
protective extracellular matrices, wield substantial influence across diverse domains such as …
Microbial biofilms: applications, clinical consequences, and alternative therapies
Biofilms are complex communities of microorganisms that grow on surfaces and are
embedded in a matrix of extracellular polymeric substances. These are prevalent in various …
embedded in a matrix of extracellular polymeric substances. These are prevalent in various …
Targeting microbial biofilms: current and prospective therapeutic strategies
H Koo, RN Allan, RP Howlin, P Stoodley… - Nature Reviews …, 2017 - nature.com
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …
chronic infections. The multifactorial nature of biofilm development and drug tolerance …
New perspectives in biofilm eradication
H Wolfmeier, D Pletzer, SC Mansour… - ACS infectious …, 2018 - ACS Publications
Microbial biofilms, which are elaborate and highly resistant microbial aggregates formed on
surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to …
surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to …
Targeting biofilms therapy: current research strategies and development hurdles
Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
Promising therapeutic strategies against microbial biofilm challenges
K Zhang, X Li, C Yu, Y Wang - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Biofilms are communities of microorganisms that are attached to a biological or abiotic
surface and are surrounded by a self-produced extracellular matrix. Cells within a biofilm …
surface and are surrounded by a self-produced extracellular matrix. Cells within a biofilm …
Novel approaches to combat bacterial biofilms
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies
S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era
M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …