The evolution of animal microRNA function
MicroRNAs (miRNAs) are a large class of small RNAs that function as negative gene
regulators in eukaryotes. They regulate diverse biological processes, and bioinformatics …
regulators in eukaryotes. They regulate diverse biological processes, and bioinformatics …
Evolution of microRNA diversity and regulation in animals
E Berezikov - Nature Reviews Genetics, 2011 - nature.com
In the past decade, microRNAs (miRNAs) have been uncovered as key regulators of gene
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
[HTML][HTML] Large-scale analysis of microRNA evolution
JA Guerra-Assunção, AJ Enright - BMC genomics, 2012 - Springer
Abstract Background In animals, microRNAs (miRNA) are important genetic regulators.
Animal miRNAs appear to have expanded in conjunction with an escalation in complexity …
Animal miRNAs appear to have expanded in conjunction with an escalation in complexity …
[HTML][HTML] The evolution and functional diversification of animal microRNA genes
N Liu, K Okamura, DM Tyler, MD Phillips, WJ Chung… - Cell research, 2008 - nature.com
Abstract microRNAs (miRNAs) are an abundant class of∼ 22 nucleotide (nt) regulatory
RNAs that are pervasive in higher eukaryotic genomes. In order to fully understand their …
RNAs that are pervasive in higher eukaryotic genomes. In order to fully understand their …
[HTML][HTML] An evolutionary perspective of animal microRNAs and their targets
MicroRNAs (miRNAs) are short noncoding RNAs that regulate gene expression through
translational inhibition or mRNA degradation by binding to sequences on the target mRNA …
translational inhibition or mRNA degradation by binding to sequences on the target mRNA …
The deep evolution of metazoan microRNAs
BM Wheeler, AM Heimberg, VN Moy… - Evolution & …, 2009 - Wiley Online Library
SUMMARY microRNAs (miRNAs) are approximately 22‐nucleotide noncoding RNA
regulatory genes that are key players in cellular differentiation and homeostasis. They might …
regulatory genes that are key players in cellular differentiation and homeostasis. They might …
[HTML][HTML] MicroRNA function in animal development
E Wienholds, RHA Plasterk - FEBS letters, 2005 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally
regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been …
regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been …
Evidence for a microRNA expansion in the bilaterian ancestor
Understanding how animal complexity has arisen and identifying the key genetic
components of this process is a central goal of evolutionary developmental biology. The …
components of this process is a central goal of evolutionary developmental biology. The …
Small but influential: the role of microRNAs on gene regulatory network and 3′ UTR evolution
MicroRNAs (miRNAs) are endogenous∼ 22 nucleotide noncoding RNAs that regulate the
expression of complementary messenger RNAs (mRNAs). Thousands of miRNA genes …
expression of complementary messenger RNAs (mRNAs). Thousands of miRNA genes …
Species‐specific micro RNA regulation influences phenotypic variability: Perspectives on species‐specific microRNA regulation
E Mor, N Shomron - Bioessays, 2013 - Wiley Online Library
Phenotypic divergence among animal species may be due in part to species‐specific (SS)
regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs” …
regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs” …