Epigenetics is the study of heritable and stable changes in gene expression that occur
through alterations in the chromosome rather than in the DNA sequence. Despite not directly …

The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …

Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …

Epigenetic regulations play a crucial role in the expression of various genes that are
important in the normal cell function. Any alteration in these epigenetic mechanisms can …

Epigenetics is the study of heritable changes in gene expression that are not mediated at the
DNA sequence level. Molecular mechanisms that mediate epigenetic regulation include …

In the past few years, there has been a nascent convergence of scientific understanding of
inherited human diseases with epigenetics. Identified epigenetic processes involved in …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

In eukaryotic cells, the DNA molecule is found in the form of a nucleoprotein complex named
chromatin. The basic unit of the chromatin is the nucleosome, which comprises 147 base …

In the nuclei of eukaryotic cells, DNA wraps around the octamer of histone proteins to form
the nucleosome, in a structure like 'beads on a string', which makes up the basic unit of …

Histones, the proteins that package eukaryotic genomes into chromatin, are subject to a
huge number and variety of covalent modifications. In the past few years, genomic …