The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments

IRA Mackenzie, R Rademakers - Neurogenetics, 2007 - Springer
The past year has seen a number of significant advances in our understanding of the
neuropathological and molecular genetic basis of frontotemporal lobar degeneration …

The genetics of frontotemporal lobar degeneration

R Rademakers, M Hutton - Current neurology and neuroscience reports, 2007 - Springer
The clinical disorders associated with frontotemporal lobar degeneration (FTLD) are
increasingly recognized as an important cause of early-onset dementia. Patients usually …

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

NJ Cairns, EH Bigio, IRA Mackenzie, M Neumann… - Acta …, 2007 - Springer
The aim of this study was to improve the neuropathologic recognition and provide criteria for
the pathological diagnosis in the neurodegenerative diseases grouped as frontotemporal …

Loss of progranulin function in frontotemporal lobar degeneration

M Cruts, C Van Broeckhoven - Trends in Genetics, 2008 - cell.com
Frontotemporal lobar degeneration (FTLD) represents a collection of neurodegenerative
diseases of frontal and temporal brain regions. It has long been associated with mutations in …

Genetics of frontotemporal lobar degeneration

D Galimberti, E Scarpini - Frontiers in neurology, 2012 - frontiersin.org
Frontotemporal lobar degeneration (FTLD), the most frequent neurodegenerative disorder
with a presenile onset, presents with a spectrum of clinical manifestations, ranging from …

Update on recent molecular and genetic advances in frontotemporal lobar degeneration

EH Bigio - Journal of Neuropathology & Experimental …, 2008 - academic.oup.com
Great strides have been made in the last 2 years in the field of frontotemporal lobar
degeneration (FTLD), particularly with respect to the genetics and molecular biology of FTLD …

Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia

JS Snowden, SM Pickering-Brown, IR Mackenzie… - Brain, 2006 - academic.oup.com
Frontotemporal lobar degeneration (FTLD) refers to a focal, non-Alzheimer form of cerebral
degeneration that encompasses the distinct clinical syndromes of frontotemporal dementia …

The genetics and neuropathology of frontotemporal lobar degeneration

A Sieben, T Van Langenhove, S Engelborghs… - Acta …, 2012 - Springer
Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders
characterized by disturbances of behavior and personality and different types of language …

The complex aetiology of frontotemporal lobar degeneration

SM Pickering-Brown - Experimental neurology, 2007 - Elsevier
Frontotemporal lobar degeneration (FTLD) is now a widely recognised form of dementia.
This heterogeneous disease has been of particular interest to geneticists due to its high rate …

Frontotemporal lobar degeneration with ubiquitin-positive inclusions: a molecular genetic update

J Van Der Zee, I Gijselinck, D Pirici… - Neurodegenerative …, 2007 - karger.com
Frontotemporal lobar degeneration (FTLD) is a clinically, pathologically and genetically
highly complex disorder. In the last few years enormous progress has been made in …