Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma

W Yin, H Zhu, J Tan, Z Xin, Q Zhou, Y Cao, Z Wu… - Cancer Cell …, 2021 - Springer
Background Gliomas account for the majority of fatal primary brain tumors, and there is much
room for research in the underlying pathogenesis, the multistep progression of glioma, and …

High expression of stromal signatures correlated with macrophage infiltration, angiogenesis and poor prognosis in glioma microenvironment

Y Tian, Y Ke, Y Ma - PeerJ, 2020 - peerj.com
Glioma is one of the most fatal tumors in central nervous system. Previous studies gradually
revealed the association between tumor microenvironment and the prognosis of gliomas …

[HTML][HTML] MYD88 is a potential prognostic gene and immune signature of tumor microenvironment for gliomas

Q Guo, X Xiao, J Zhang - Frontiers in oncology, 2021 - frontiersin.org
Purpose To explore the profiles of immune and stromal components of the tumor
microenvironment (TME) and their related key genes in gliomas. Methods We applied …

[HTML][HTML] Construction of a prognostic gene signature associated with immune infiltration in glioma: a comprehensive analysis based on the cgga

X Gong, L Liu, J Xiong, X Li, J Xu, Y Xiao, J Li… - Journal of …, 2021 - hindawi.com
Background. Tumor microenvironment (TME) is closely related to the progression of glioma
and the therapeutic effect of drugs on this cancer. The aim of this study was to develop a …

[HTML][HTML] Multi-omics analysis predicts fibronectin 1 as a prognostic biomarker in glioblastoma multiforme

F Kabir, MNH Apu - Genomics, 2022 - Elsevier
Glioblastoma (GBM) is one of the most malignant and intractable central nervous system
tumors with high recurrence, low survival rate, and poor prognosis. Despite the advances of …

Identification of immune cell infiltration and immune-related genes in the tumor microenvironment of glioblastomas

S Huang, Z Song, T Zhang, X He, K Huang… - Frontiers in …, 2020 - frontiersin.org
Glioblastoma (GBM) is one of the most prevalent malignant brain tumors with poor
prognosis. Increasing evidence has revealed that infiltrating immune cells and other stromal …

[HTML][HTML] ANXA1 as a prognostic and immune microenvironmental marker for gliomas based on transcriptomic analysis and experimental validation

Z Lin, M Wen, E Yu, X Lin, H Wang, J Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
The tumor microenvironment (TME) plays an important role in the growth and invasion of
glioma. This study aimed to analyze the composition of the immune microenvironment in …

[HTML][HTML] Screening TCGA database for prognostic genes in lower grade glioma microenvironment

J Ni, S Liu, F Qi, X Li, S Yu, J Feng… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
Background To identify prognostic hub genes which associated with tumor
microenvironment (TME) in lower grade glioma (LGG) of central nervous system. Methods …

Comprehensive analysis of inflammatory response–related genes, and prognosis and immune infiltration in patients with low-grade glioma

T Han, Z Zuo, M Qu, Y Zhou, Q Li… - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: Although low-grade glioma (LGG) has a good prognosis, it is prone to
malignant transformation into high-grade glioma. It has been confirmed that the …

The prognostic value of EMT in glioma and its role in the glioma immune microenvironment

W Ning, Z Qiu, X Ji, X Wang, Y An, S Wang… - Journal of Molecular …, 2020 - Springer
Diffuse glioma is the deadliest form of brain cancer, and the median survival of grade IV
glioma (glioblastoma, GBM) is no more than 2 years even with maximal surgical resection …