Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting∼ 3% of
children worldwide. AIS significantly impacts national health in the US alone, creating …

Adolescent idiopathic scoliosis (AIS) is the most common pediatric spinal deformity. Several
AIS susceptibility loci have been identified; however, they could explain only a small …

Although the exact etiology of adolescent idiopathic scoliosis is still undefined, genetic
factors play an important role. Some patients have familial genetic disease that appears to …

Idiopathic scoliosis (IS), the most common spinal deformity, affects otherwise healthy
children and adolescents during growth. The aetiology is still unknown, although genetic …

Adolescent idiopathic scoliosis (AIS) is an unexplained and common spinal deformity seen
in otherwise healthy children. Its pathophysiology is poorly understood despite intensive …

Idiopathic scoliosis in the adolescent period is a complex genetic disorder of high
prevalence and extreme variability. Epidemiological approaches have confirmed the genetic …

Adolescent idiopathic scoliosis (AIS) is a structural deformity of the spine affecting millions of
children. As a complex disease, the genetic aetiology of AIS remains obscure. Here we …

Idiopathic scoliosis is one of the most common complex genetic disorders of the
musculoskeletal system. The clinical parameters relating to onset, curve progression, and …

Scoliosis is a lateral curvature of the spine that is frequently encountered by healthcare
professionals. Scoliosis has historically been categorized into congenital, neuromuscular …

Purpose Idiopathic scoliosis is a complex developmental syndrome defined by an abnormal
structural curvature of the spine. High treatment costs, chronic pain/discomfort, and the need …