[PDF][PDF] Method Validation of a Tricyclic Antidepressant Drug Panel in Urine by LC-MS/MS

CN Lin, JEM Juenke… - CLINICAL …, 2012 - pdfs.semanticscholar.org
To evaluate accuracy, drug-free urine was pooled and used as a matrix to spike 22 samples
with TCA at different concentrations. An additional 33 patient samples were collected and …

Method validation of a tricyclic antidepressant drug panel in urine by UPLC-MS/MS

CN Lin, JEM Juenke… - Annals of Clinical & …, 2014 - Assoc Clin Scientists
Tricyclic antidepressant (TCA) drugs are also used as adjunctive therapy to treat chronic
pain. To monitor patient compliance to therapy, urine specimens may be preferred since …

Interpreting tricyclic antidepressant measurements in urine in an emergency department setting: comparison of two qualitative point-of-care urine tricyclic …

SEF Melanson, EL Lewandrowski… - Journal of analytical …, 2007 - academic.oup.com
Patients taking tricyclic antidepressants (TCA) can experience toxicity or severe side effects.
As a rapid and less technically demanding alternative to quantitative serum analysis, most …

Detection and quantification of tricyclic antidepressants and other psychoactive drugs in urine by HPLC/MS/MS for pain management compliance testing

JL Poklis, CE Wolf, A Goldstein… - Journal of Clinical …, 2012 - Wiley Online Library
A sensitive, specific, and rapid high‐pressure liquid chromatography/mass
spectrometry/mass spectrometry method was developed for the quantitation of 11 tricyclic …

Systematic development of an UPLC–MS/MS method for the determination of tricyclic antidepressants in human urine

EE Chambers, MJ Woodcock, JP Wheaton… - … of pharmaceutical and …, 2014 - Elsevier
Tricyclic antidepressants have been prescribed for the treatment of depression and other
disorders since their discovery in the 1950s but have been replaced in recent decades by …

Development and Validation of an Analytical Methods for Quantification of 15 Non-Tricyclic Antidepressants in Serum with UPLC-MS/MS

SDT Resende - 2015 - search.proquest.com
Objective: Non-tricyclic antidepressants are often encountered in overdose cases, and for
some of them therapeutic monitoring might be warranted. Therefore we developed and …

Development and validation of an analytical method for quantification of 15 non-tricyclic antidepressants in serum with UPLC-MS/MS

S Resende, C Deschrijver, E van de Velde… - … Analytique et Clinique, 2016 - Elsevier
Objective Non-tricyclic antidepressants are often encountered in overdose cases, and for
some of them therapeutic monitoring might be warranted. Therefore, we developed and …

Urinary tricyclic antidepressant screening: comparison of results obtained with Abbott FPIA reagents and Syva EIA reagents

GM Meenan, S Barlotta, M Lehrer - Journal of analytical …, 1990 - academic.oup.com
Human urine was tested for tricyclic antidepressants with fluorescence polarization
immunoassay (FPIA) reagents on Abbott's ADx system and with EIA reagents on Syva's ETS …

Evaluation of Bio-Rad TOX/See™ Rapid Urine Drug Screen Test for Screening Tricyclic Antidepressants in Emergency Toxicology

R Lerner, W Link, J Lai - researchgate.net
Intoxication by Tricyclic Antidepressants (TCA) is a frequent diagnosis in emergency rooms
worldwide. Liquid chromatography/Mass Spectrometry (LC/MS)[1] and high performance …

Developing and validating a fast and accurate method to quantify 18 antidepressants in oral fluid samples using SPE and LC–MS-MS

SS Shin, D Borg, R Stripp - Journal of Analytical Toxicology, 2020 - academic.oup.com
Antidepressant drugs are one of the most widely used medicines for treating major
depressive disorders for long time periods. Oral fluid (OF) testing offers an easy and non …