RISUG: An intravasal injectable male contraceptive

NK Lohiya, I Alam, M Hussain, SR Khan… - Indian Journal of …, 2014 - journals.lww.com
Over the last two decades RISUG has been drawing attention in the field of male
contraception. It promises to sterile men for a period of up to 10-15 years. According to …

RISUG® as a male contraceptive: journey from bench to bedside

B Khilwani, A Badar, AS Ansari, NK Lohiya - Basic and Clinical Andrology, 2020 - Springer
Even after decades of research men still lack reliable and reversible contraceptive methods
comparable to female methods of contraception. Traditional methods of male contraception …

Summer savory (Satureja hortensis) can reduce spermatotoxic effects of doxorubicin in rats

A Shalizar Jalali, G Najafi, P Rahimzadeh - Caspian Journal of …, 2015 - caspjrm.ir
Methods: Male Wistar rats were randomly divided into four groups of six rats each. DOX was
administered to two groups of rats in 5 equal intraperitoneal injections over a period of 4 …

Effects of ulipristal acetate on sperm DNA fragmentation during in vitro incubation

MJ Munuce, J Cicaré, C Zumoffen, A Caille… - … European Journal of …, 2013 - Taylor & Francis
Objective Ulipristal acetate (UPA) acts as an emergency contraceptive by inhibiting
ovulation. This study explores possible additional effects on the fragmentation of sperm DNA …

[PDF][PDF] Evaluation of testicular cytotoxicity and genotoxicity of sofosbuvir and sofosbuvir-ribavirin in the adult male albino rats

WB El-Kholy, MA Faried, RM Salama, MM El-Fiky… - Eur. j. anat, 2019 - eurjanat.com
Hepatitis C is a widely distributed problem all over the world, especially Egypt. Chronically
infected people develop serious liver disease and now it is the most common cause for liver …

Phase II clinical trial of a vas deferens injectable contraceptive for the male

SK Guha, G Singh, S Ansari, S Kumar, A Srivastava… - Contraception, 1997 - Elsevier
Following up on an earlier clinical trial demonstrating the safety of an intra-vas deferens
injection of a contraceptive drug named Risug, comprised of styrene maleic anhydride …

[HTML][HTML] The adverse effects of the methoxsalen and ultraviolent A radiation on spermatogenesis in mice

M Farhadi, HM Kouchesfahani… - Iranian Journal of …, 2015 - ncbi.nlm.nih.gov
Background: Different investigation showed that 5-methoxypsoralen and 8-methoxypsoralen
reduce birth rates in the rats. Objective: In this study we worked out the effect of methoxsalen …

[PDF][PDF] A proton NMR study of the effect of a new intravasal injectable male contraceptive RISUG on seminal plasma metabolites

U Sharma, K Chaudhury, NR Jagannathan… - REPRODUCTION …, 2001 - academia.edu
There is a need to develop a suitable male contraceptive for population control programmes.
The current unavailability of an ideal male contraceptive is due to the lack of one or more …

A short-term evaluation of semen and accessory sex gland function in phase III trial subjects receiving intravasal contraceptive RISUG

SP Chaki, HC Das, MM Misro - Contraception, 2003 - Elsevier
Following the intravasal injection of a new male contraceptive RISUG (reversible inhibition
of sperm under guidance) in volunteers, routine semen analysis, semen biochemistry and …

Assessment of the toxicity of different antiretroviral drugs and their combinations on Sertoli and Leydig cells

M Baysal, AB Karaduman… - Drug and Chemical …, 2024 - Taylor & Francis
The human immunodeficiency virus continues to pose a significant global public health
challenge, affecting millions of individuals. The current treatment strategy has incorporated …