HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years

T Matsuzaki, M Nakagawa, M Nagai, K Usuku… - Journal of …, 2001 - Springer
To clarify clinical and laboratory findings that may be related to the pathomechanism of
HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed these …

[HTML][HTML] High Expression of CD244 and SAP Regulated CD8+ T Cell Responses of Patients with HTLV-I Associated Neurologic Disease

Y Enose-Akahata, E Matsuura, U Oh… - PLoS …, 2009 - journals.plos.org
HTLV-I-specific CD8+ T cells have been characterized with high frequencies in peripheral
blood and cerebrospinal fluid and production of proinflammatory cytokines, which contribute …

[HTML][HTML] Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis

F Martin, H Castro, C Gabriel, A Adonis… - PLoS neglected …, 2012 - journals.plos.org
Introduction Patients with HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) become progressively impaired, with chronic pain, immobility and bladder …

Long term, high dose interferon-alpha treatment in HTLV-I-associated myelopathy/tropical spastic paraparesis: a combined clinical, virological and immunological …

K Yamasaki, J Kira, Y Koyanagi, Y Kawano… - Journal of the …, 1997 - Elsevier
The efficacy of long-term, high dose interferon-α (IFN-α) therapy was studied in seven
patients with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). IFN-α …

Degenerate specificity of HTLV-1–specific CD8+ T cells during viral replication in patients with HTLV-1–associated myelopathy (HAM/TSP)

R Kubota, Y Furukawa, S Izumo… - Blood, The Journal of …, 2003 - ashpublications.org
Human T-lymphotropic virus type 1 (HTLV-1)–associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is an inflammatory neurologic disease caused by HTLV-1 infection …

[HTML][HTML] Efficacy of prosultiamine treatment in patients with human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: results from an open …

T Nakamura, T Matsuo, T Fukuda, S Yamato… - BMC medicine, 2013 - Springer
Background Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical
spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by motor dysfunction …

[HTML][HTML] Human T lymphotropic virus type 1 (HTLV-1) proviral load induces activation of T-lymphocytes in asymptomatic carriers

R Coutinho, MFR Grassi, AB Korngold… - BMC Infectious …, 2014 - Springer
Background High HTLV-1 proviral load (PVL) is mainly found in infected individuals with
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However one third …

[引用][C] Neopterin in cerebrospinal fluid: A useful marker for diagnosis of HTLV‐I‐associated myelopathy/tropical spastic paraparesis

M Nomoto, Y Utatsu, Y Soejima, M Osame - Neurology, 1991 - AAN Enterprises
An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical
spastic paraparesis (HAM/TSP) focusing on clinical and laboratory biomarkers …

Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy

D Hayashi, R Kubota, N Takenouchi, T Nakamura… - Journal of …, 2008 - Springer
Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a slowly progressive, inflammatory disease of the central nervous …

Histopathological analysis of four autopsy cases of HTLV-I-associated myelopathy/tropical spastic paraparesis: inflammatory changes occur simultaneously in the …

MM Aye, E Matsuoka, T Moritoyo, F Umehara… - Acta …, 2000 - Springer
Although brain lesions have been described in some cases with HTLV-I-associated
myelopathy/tropical spastic paraparesis (HAM/TSP), little is known about the nature of brain …