Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation

F Lin, F van Rhee, JM Goldman, NC Cross - 1996 - ashpublications.org
We prospectively studied 98 chronic myeloid leukemia (CML) patients after bone marrow
transplantation by competitive polymerase chain reaction to detect and quantify leukemia …

Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation

NC Cross, L Feng, A Chase, J Bungey, TP Hughes… - 1993 - ashpublications.org
We have developed a competitive polymerase chain reaction (PCR) titration assay that
estimates the number of BCR-ABL transcripts in chronic myeloid leukemia patients to …

Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define …

J Kaeda, D O'shea, RM Szydlo, E Olavarria, F Dazzi… - Blood, 2006 - ashpublications.org
We identified 243 patients with Philadelphia (Ph) chromosome–positive chronic myeloid
leukemia (CML) who had BCR-ABL transcripts monitored by quantitative reverse …

The significance of bcr-abl molecular detection in chronic myeloid leukemia patients “late,” 18 months or more after transplantation

JP Radich, T Gooley, E Bryant… - Blood, The Journal …, 2001 - ashpublications.org
The bcr-abl chimeric messenger RNA is frequently detected in chronic myeloid leukemia
(CML) patients after bone marrow transplantation. It was previously reported that the relapse …

Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.

CL Sawyers, L Timson, ES Kawasaki… - Proceedings of the …, 1990 - National Acad Sciences
Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Estimating the relapse stage in chronic myeloid leukaemia patients after allogeneic stem cell transplantation by the amount of BCR‐ABL fusion transcripts detected …

AH Elmaagacli, A Freist, M Hahn… - British journal of …, 2001 - Wiley Online Library
We have used a new single‐step real‐time reverse transcription polymerase chain reaction
(RT‐PCR) method to quantify BCR‐ABL transcripts, thereby estimating the relapse stage in …

Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …

K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time'quantitative RT-PCR assay

C Preudhomme, F Revillion, A Merlat, L Hornez… - Leukemia, 1999 - nature.com
Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …

R Delage, RJ Soiffer, K Dear, J Ritz - 1991 - ashpublications.org
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …