Sperm characteristics and teratology in rats following vas deferens occlusion with RISUG and its reversal

NK Lohiya, R Suthar, A Khandelwal… - … journal of andrology, 2010 - Wiley Online Library
The functional success of the reversal of vas occlusion by styrene maleic anhydride
(RISUG), using the solvent vehicle, Dimethyl Sulphoxide (DMSO), has been investigated …

Contraception with RISUG® and functional reversal through DMSO and NaHCO3 in male rabbits

AS Ansari, A Badar, K Balasubramanian… - Asian journal of …, 2017 - journals.lww.com
The study aimed to evaluate reversal of short-and long-term vas occlusion with reversible
inhibition of sperm under guidance (RISUG) using dimethyl sulfoxide (DMSO) and sodium …

Relative suitability of DMSO and NaHCO3 for reversal of RISUG® induced long‐term contraception

AS Ansari, M Hussain, SR Khan, NK Lohiya - Andrology, 2016 - Wiley Online Library
Among the vas‐based methods on trial, reversible inhibition of sperm under guidance
(RISUG®), a co‐polymer of styrene and maleic anhydride is being projected as an effective …

Toxicity and mutagenicity evaluation following RISUG contraception reversal in rats

AS Ansari, M Hussain, SR Khan… - International …, 2018 - journals.sagepub.com
Reestablishment of fertility, after a male contraceptive method, is of great concern. In this
context, RISUG (Reversible Inhibition of Sperm Under Guidance) has been evaluated for its …

Status of spermatogenesis and sperm parameters in langur monkeys following long‐term vas occlusion with styrene maleic anhydride

PK Mishra, B Manivannan, N Pathak… - Journal of …, 2003 - Wiley Online Library
Vas occlusion by styrene maleic anhydride (SMA), trade name RISUG (one of the promising
male contraceptive procedures currently in phase III clinical trials), at 60 mg/vas deferens …

Preclinical evaluation for noninvasive reversal following long-term vas occlusion with styrene maleic anhydride in langur monkeys

NK Lohiya, B Manivannan, PK Mishra, S Sriram… - Contraception, 2005 - Elsevier
A preclinical evaluation for reversal through a noninvasive approach following long-term vas
occlusion with styrene maleic anhydride (SMA) has been attempted in langur monkeys at …

Safety evaluation through genotoxicity and apoptotic markers following RISUG® induced contraception and its reversal in male rabbits

AS Ansari, A Badar, NK Lohiya - Reproductive Toxicology, 2018 - Elsevier
The safety evaluation following vas occlusion with RISUG® and its reversal with DMSO and
NaHCO 3, using genotoxicity tests and apoptotic marker assays, was carried out in rabbits …

[PDF][PDF] Quantitative (stereological) study of the effects of vasectomy on spermatogenesis in rhesus monkeys (Macaca mulatta)

B Peng, RD Zhang, XS Dai, XZ Deng… - REPRODUCTION …, 2002 - researchgate.net
Vasectomy has been used widely for more than a century as a contraceptive method
(especially since the late 1960s and early 1970s), occasionally for compulsory male …

Rapid disappearance of spermatozoa after vasal occlusion in the dog

JD Schiff, PS Li, PN Schlegel… - Journal of …, 2003 - Wiley Online Library
The reproductive system of the male dog is unusual in that the seminal vesicles and
bulbourethral glands are absent. Therefore, we chose the dog as a model to evaluate the …

Relationship between vas occlusion techniques and recanalization

SQ Li, B Xu, YH Hou, CH Li… - Advances in …, 1994 - pubmed.ncbi.nlm.nih.gov
PIP: In southwest China between April, 1988, and March, 1990, providers at 5 family
planning centers in Sichuan, Guangxi, Yunnan, and Guizhou provinces performed 2713 …