Ruminants have a semi-invasive placenta, which possess highly vascularized placentomes
formed by maternal endometrial caruncles and fetal placental cotyledons and required for …

A central determinant of pregnancy success is proper development of the conceptus
(embryo/fetus and associated extraembryonic membranes including the placenta). Although …

The placenta is crucial for a successful pregnancy and the health of both the fetus and the
pregnant woman. However, how the human trophoblast lineage is regulated, including the …

Successful establishment and maintenance of pregnancy can be attained only through
optimum conceptus-maternal cross talk. Despite significant progress in our understanding of …

In the present study, we used the global transcriptome profile approach to identify
dysregulated genes, molecular pathways, and molecular functional alterations in bovine …

The mechanisms underlying detachment of foetal membranes after birth in cows are still
unclear. To address this problem in a systematic manner, we performed the first holistic …

Bidirectional communication between the developing conceptus and endometrium is
essential for pregnancy recognition and establishment in ruminants. We dissect the …

The fusion of villous cytotrophoblasts into the multinucleated syncytiotrophoblast is critical
for the essential functions of the mammalian placenta. Using RNA-Seq gene expression and …

Cell to cell interaction plays a pivotal role in the regulation of placentogenesis and exchange
of stage-specific developmental signals between the fetal and maternal units. Specifically …

The objective was to characterize the transcriptome profile of in vivo–derived female
embryos competent to establish and maintain gestation. Blastocysts from superovulated …