Erlotinib is an essential drug for the clinical treatment of non-small cell lung cancer,
pancreatic cancer, and other cancers. Erlotinib tends to be conformation A rather than the …

In this work, for the first time, we have investigated the structural and optoelectronic
properties of Erlotinib hydrochloride (C 22 H 24 N 3 O 4+· Cl−)(1) anticancer drug using DFT …

In this study, we provide the first Fourier‐transform infrared absorption spectroscopy (FTIR)
and Raman spectroscopy (RS) analysis of a vibrational fingerprint of erlotinib, a drug which …

Cancer is the world's third leading cause of mortality, after only cardiovascular disease,
parasitic infection, and infectious disease, according to the World Health Organization …

Epidermal growth factor receptor (EGFR) plays an important role in cell proliferation at non-
small cell lung cancer (NSCLC). Therefore, targeted therapy of cancer via this kind of …

Erlotinib and gefitinib are quinazoline derivatives with antineoplastic properties. Usually,
intake of antineoplastic agents results in much a greater degree of oxidative stress, ie the …

Over the years, the escalation of cancer cases has been linked to the resistance, less
selectivity, and toxicity of available anticancer drugs to normal cells. Therefore, continuous …

Based on desity functional theory (DFT), two functional and basis sets B3LYP/6-311G (d, p)
and B3PW91/6-311G (d, p) were used to optimize the structure of gefitinib. On this basis …

Erlotinib is a BCS (biopharmaceutical classification system) class II drug used for the
treatment of non-small cell lung cancer. There is an urgent need to obtain new solid forms of …

Molecular structure, chemical and physical reactivity, spectroscopic behavior, intermolecular
interactions play an important role in understanding the biological nature of pharmaceutical …