Long-acting β-agonists: anti-inflammatory properties and synergy with corticosteroids in asthma

TL Remington, B DiGiovine - Current opinion in pulmonary …, 2005 - journals.lww.com
Current asthma treatment recommendations are based on clinical trials demonstrating
improved clinical outcomes of combination ICS plus LABA over ICS alone. Whether LABA …

Antiinflammatory effects of long-acting β2-agonists in patients with asthma: a systematic review and metaanalysis

A Sindi, DC Todd, P Nair - Chest, 2009 - Elsevier
Background Long-acting β 2-agonists are recommended as add-on therapy to
antiinflammatory treatment in patients with chronic persistent asthma. Results from individual …

The future of the long-acting beta-adrenergic bronchodilators in the treatment of asthma

LE Mansfield - Allergy and asthma proceedings, 2008 - ingentaconnect.com
The combination of long-acting beta-agonist (LABA) bronchodilators with inhaled
corticosteroids (ICSs) has been shown to be an extremely effective treatment for asthma …

Benefit-Risk Assessment of Long-Acting β2-Agonists in Asthma

CM Jackson, B Lipworth - Drug Safety, 2004 - Springer
The use of a regular long-acting β 2-adrenoceptor agonists (β 2-agonists; LABA) is now
established in asthma guidelines as the preferred option for second-line controller therapy in …

[HTML][HTML] Inhaled corticosteroid and long-acting β2-agonist pharmacological profiles: effective asthma therapy in practice

M Tamm, DH Richards, B Beghé, L Fabbri - Respiratory medicine, 2012 - Elsevier
Fixed-dose combinations of inhaled corticosteroids (ICSs) and long-acting β2-agonists
(LABAs) have been used to manage asthma for several years. They are the preferred …

Advances in Asthma and COPD Treatment: Combination Therapy with Inhaled Corticosteroids and Long-Acting β2-Agonists.

A Miller-Larsson, O Selroos - Current pharmaceutical design, 2006 - ingentaconnect.com
Asthma treatment guidelines advocate the use of long-acting β2-agonists (LABA) in addition
to inhaled corticosteroids (ICS) in patients whose asthma is uncontrolled by ICS alone …

Long-acting beta-agonists in adult asthma: evidence that these drugs are safe

HS Nelson - Primary Care Respiratory Journal, 2006 - nature.com
If asthma is not controlled with low-dose inhaled corticosteroids (ICS), by far the best next
step is the addition of a long-acting, inhaled beta-agonist (LABA). Questions regarding the …

Safety of long-acting β agonists for the treatment of asthma: clearing the air

GJ Rodrigo, JA Castro-Rodríguez - Thorax, 2012 - thorax.bmj.com
Concerns about the safety of long-acting β2-agonist (LABA) therapy, has led to the
appearance of multiple publications and recommendations. This review critically examines …

Safety of long-acting β2-agonists in the treatment of asthma

M Cazzola, MG Matera - Therapeutic Advances in …, 2007 - journals.sagepub.com
Several studies suggested an association between the regular use of β 2-agonists and
asthma deaths. Whether this association represents adverse effects of β-agonist use or is …

Safety of regular use of long-acting beta agonists as monotherapy or added to inhaled corticosteroids in asthma. A systematic review

GJ Rodrigo, VP Moral, LG Marcos… - Pulmonary …, 2009 - Elsevier
BACKGROUND: Safety of long-acting beta agonists (LABA) has been questioned and
recent evidence suggested a detrimental effect on asthma control as well as an increased …