Background: Regulatory bodies including the European Medicines Agency register
medications (formulation, route of administration) for specific clinical indications. Once …

Background: The 'off-label'use of a drug beyond the specifications of its Marketing
Authorization is widespread in palliative care. It is legal, but there are implications for …

Background: Off-label-use is an indispensable element of palliative medicine. Up to one
third of all drugs are prescribed beyond their licence. It is challenging to find the right …

Background: Drug use beyond the licence (off-label use, off-label drug use) is a common
practice in palliative care and respective recommendations can often be identified in the …

Objectives The use of drugs beyond their marketing authorisation, that is, off-label use, is
common practice in palliative care with over 70% of off-label use having little or no scientific …

Off-label prescription is part of routine care in palliative medicine, but no information is
available about the situation in Italy. A cross-sectional observational survey was undertaken …

Off-label prescribing is an integral part of contemporary medicine. Many patients benefit
when they receive drugs or devices under circumstances not specified on the label …

▪ Abstract Off‐label medication use is common practice, particularly in difficult to treat
patients who have already tried commonly accepted medication unsuccessfully. Health …

Background: Medicine use is considered off-label when used for an indication, at a dose, via
a route of administration or in a patient group not included in the approved product …

Off-label prescribing occurs when a practitioner prescribes a drug for a use, or in a manner,
not listed in the 'approved product information'(API) for that drug. The literature suggests that …