The hypothesis that only melanosomal catecholic amino acids contribute to melanin
formation was tested by studying adult bovine eyes in which pigment synthesis is …

The concentration of dopa, dopamine and cysteinyldopa were measured in various parts of
the mature bovine eye, using a fluorescent assay. Special attention was paid to …

To explore the possibility that dopa and 5-S-cysteinyldopa, precursors of melanin, can be
produced in non-melanogenic tissues, this study examined the contents of the free and …

Dopa and 5-S-cysteinyldopa levels in serum of albino, red, and black guinea-pigs were
quantified. The levels of both amino acids were lower in the albino than in the pigmented …

The concentrations of dopa and 5-S-cysteinyldopa were determined in the various cell frac-
tions of Harding-Passey melanomas. Dopa was present in larger amounts than was 5-S …

Cultured melanoma cells have been of great value in the study of pigment metabolism. IGR
1 human melanoma cells, established by Dr Christian Aubert, produce melanin in large …

Previous studies have demonstrated a specific cytoplasmic fluorescence in human
melanocytes, as well as in pigmented nevi and in malignant melanomas, when the …

The tyrosinase activity in melanin‐forming tissues was investigated in a series of rats (6 days
to 1 year old), one cat 30 days old, and one 4 month old human fetus. The technique used …

Electron microscopic autoradiography was used to investigate the relationship between
melanin formation and thiol incorporation in premelanosomes of genetically defined chick …

S-Cysteinyldopa, an amino acid formed by nucleophilic addition of cysteine to dopaquinone,
has been detected in the ganglion stellatum of the cow in amounts varying between 21 and …