CO2 environment influences the growth of cultured human cancer cells dependent on insufflation pressure

CN Gutt, ZG Kim, D Hollander, T Bruttel, M Lorenz - Surgical endoscopy, 2001 - Springer
Background Experimental and clinical studies, have suggested that the CO 2
pneumoperitoneum influences the development of intraabdominal tumor dissemination and …

Intraperitoneal tumor growth is influenced by pressure of carbon dioxide pneumoperitoneum

PH Wittich, EW Steyerberg, SHP Simons… - Surgical …, 2000 - Springer
Background: Several studies have indicated that the carbon dioxide (CO 2)
pneumoperitoneum during laparoscopy plays a role in the pathogenesis of port-site …

Influence of CO2 pneumoperitoneum during laparoscopic surgery on cancer cell growth

S Takiguchi, N Matsuura, Y Hamada, E Taniguchi… - Surgical …, 2000 - Springer
Background CO 2 pneumoperitoneum provides a new surgical environment to treat
malignant disease. The purpose of this study was to investigate the influence of CO 2 …

Pneumoperitoneum with carbon dioxide enhances liver metastases of cancer cells implanted into the portal vein in rabbits

H Ishida, N Murata, H Yamada, H Nakada, I Takeuchi… - Surgical …, 2000 - Springer
Background: Little is known about the role of the CO 2 pneumoperitoneum on tumor cells
that spread from the portal system into the liver during laparoscopic surgery for …

Pneumoperitoneum with carbon dioxide stimulates growth of malignant colonic cells

CA Jacobi, R Sabat, B Böhm, HU Zieren, HD Volk… - Surgery, 1997 - Elsevier
Background. Port-site recurrences have often been reported after laparoscopic surgery for
malignant disease, and the pathogenesis is unknown. Whether different gases used to …

Effect of pneumoperitoneum induced by carbon dioxide and air on tumor load in a rat model

O Lundberg, A Kristoffersson - World journal of surgery, 1998 - Springer
Laparoscopic surgery for malignant disease is highly controversial mainly due to the large
number of abdominal wall metastases being reported. Previous experimental studies have …

The effect of CO2 pneumoperitoneum on the growth of a solid colon carcinoma in rats

M Pauwels, P Lauwers, J Hendriks, A Hubens… - Surgical …, 1999 - Springer
Background: In order to investigate the effect of carbon dioxide (CO 2) pneumoperitoneum
on solid colon carcinomas, we used a colon anastomosis tumor model in 30 male syngeneic …

Increased insufflation pressure enhances the development of liver metastasis in a mouse laparoscopy model

H Ishida, D Hashimoto, H Nakada, I Takeuchi… - Surgical Endoscopy And …, 2002 - Springer
Background: The effect of different insufflation pressures and durations of CO2
pneumoperitoneum on the growth of liver metastasis was investigated in a mouse model …

Increased insufflation pressure enhances the development of liver metastasis in a mouse laparoscopy model

H Ishida, N Murata, Y Idezuki - World journal of surgery, 2001 - Wiley Online Library
Despite the widespread use of laparoscopic techniques for colorectal cancer surgery, little is
known about the potential risk of liver metastasis following CO2 pneumoperitoneum. We …

Effect of carbon dioxide pneumoperitoneum on tissue blood flow in the peritoneum, rectus abdominis, and diaphragm muscles

Y Yavuz, K Rønning, O Lyng, JE Grønbech… - Surgical Endoscopy And …, 2003 - Springer
Background: Changes in local blood flow may play a role in the pathogenesis of port-site
metastasis. This study aimed to investigate the effect of pneumoperitoneum induced by …